Abstract
A new method of image reconstruction for single-photon emission computer tomography (SPECT) in a proportional scattering medium has been suggested. Detector counts have been obtained by Monte Carlo simulation using the Geant4 nuclear physics software package, which has eliminated the need for applying a real tomograph, radiopharmaceuticals (radiotracers), and a SPECT phantom. Detector counts obtained using Geant4 are virtually the same as those that could be obtained in a full-scale experiment carried out in a real scattering medium. The influence of the absorbing and scattering capabilities of 13 different substances modeling a medium in which the radiation source spatial distribution is submerged on the tomogram reconstruction accuracy has been studied. That this algorithm has considerable advantages for emission tomogram reconstruction over conventional one have been demonstrated.
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REFERENCES
V. V. Pikalov and T. S. Mel’nikova, Plasma Tomography (Nauka, Novosibirsk, 1995) [in Russian].
Emission Tomography: The Fundamentals of PET and SPECT, Eds. by M. N. Wernick and J. N. Aarsvold (Academic, San Diego, 2004).
S. A. Tereshchenko, Computerized Tomohraphy Techniques (Fizmatlit, Moscow, 2004) [in Russian].
J. Prekeges, Nuclear Medicine Instrumentation (Jones and Bartlett, Burlington, MA, 2012).
S. R. Cherry, J. A. Sorenson, and M. E. Phelps, Physics in Nuclear Medicine (Elsevier Health Sci., Philadelphia, 2012).
Webb’s Physics of Medical Imaging, Ed. by M. A. Flower (CRC, Boca Raton, 2012).
K. M. Case and P. F. Zweifel, Linear Transport Theory (Addison–Wesley, Reading, Mass., 1967).
A. Ishimaru, Wave Propagation and Scattering in Random Media (Academic, New York, 1978).
A. M. Kol’chuzhkin and V. V. Uchaikin, Introduction to the Theory of the Passage of Particles through Matter (Atomizdat, Moscow, 1978) [in Russian].
L. A. Apresyan and Yu. A. Kravtsov, Radiation Transfer: Statistical and Wave Aspects (Gordon and Breach, Basel, 1996).
H. H. Barrett, B. Gallas, E. Clarkson, and A. Clough, in Computational Radiology and Imaging, Eds by C. Börgers and F. Natterer (Springer, New York, 1999), p. 71.
E. M. A. Hussein, Radiation Mechanics: Principles and Practice (Elsevier, Amsterdam, 2010).
S. Bellini, M. Piacentini, C. Cafforio, and F. Rocca, IEEE Trans. Acoust., Speech, Signal Process. 27 (3), 213 (1979). https://doi.org/10.1109/TASSP.1979.1163232
O. Tretiak and C. Metz, SIAM J. Appl. Math. 39 (2), 341 (1980). https://doi.org/10.1137/0139029
G. T. Gullberg and T. F. Budinger, IEEE Trans. Biomed. Eng. 28 (2), 142 (1981). https://doi.org/10.1109/TBME.1981.324787
I. A. Hazou and D. C. Solmon, J. Math. Anal. Appl. 141 (1), 109 (1989). https://doi.org/10.1016/0022-247X(89)90209-6
P. P. Bruyant, J. Nucl. Med. 43, 1343 (2002).
S. A. Tereshchenko, Tech. Phys. 62 (9), 1293 (2017). https://doi.org/10.1134/S1063784217090250
I. M. Sobol’, Monte Carlo Numerical Methods (Nauka, Moscow, 1973) [in Russian].
G. Fishman, Monte Carlo: Concepts, Algorithms, and Applications (Springer, New York, 2013).
O. N. Vassiliev, Monte Carlo Methods for Radiation Transport: Fundamentals and Advanced Topics (Springer, New York, 2016).
J. Allison et al., IEEE Trans. Nucl. Sci. 53 (1), 270 (2006). https://doi.org/10.1109/TNS.2006.869826
S. Agostinelli et al., Nucl. Instrum. Methods Phys. Res., Sect. A 506 (3), 250 (2003). https://doi.org/10.1016/S0168-9002(03)01368-8
J. Allison et al., Nucl. Instrum. Methods Phys. Res., Sect. A 835, 186 (2016). https://doi.org/10.1016/j.nima.2016.06.125
J. Baro, J. Sempau, J. M. Fernandez-Varea, and F. Salvat, Nucl. Instrum. Methods Phys. Res., Sect. B 100, 31 (1995). https://doi.org/10.1016/0168-583X(95)00349-5
D. Sarrut et al., Med. Phys. 41 (6), 064301 (2014). https://doi.org/10.1118/1.4871617
XCOM: Photon Cross Sections Database (https:// www.nist.gov/pml/xcom-photon-cross-sections-database). https://doi.org/10.18434/T48G6X
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This study was supported by the Russian Foundation for Basic Research, grant no. 19-32-90049.
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Translated by V. Isaakyan
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Tereshchenko, S.A., Lysenko, A.Y. Reconstruction of the Radiation Source Spatial Distribution in a Proportional Scattering Medium. Tech. Phys. 66, 805–814 (2021). https://doi.org/10.1134/S1063784221050236
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DOI: https://doi.org/10.1134/S1063784221050236