Skip to main content
SpringerLink
Log in

Dimethyl sulfoxide-induced dehydration of the intermembrane space of dipalmitoylphosphatidylcholine multilamellar vesicles: Neutron and synchrotron diffraction study

  • Surface, Thin Films
  • Published:
Crystallography Reports Aims and scope Submit manuscript

Abstract

Small-angle neutron scattering spectra of a polydispersed population of dipalmitoylphosphatidylcholine (DPPC) unilamellar vesicles in heavy water in the presence of dimethyl sulfoxide (DMSO) are analyzed by means of the separated form-factor method. An increase in the mole fraction of DMSO in water from 0 to 15% was shown to lead to an increase in the thickness of the bilayer to the characteristics repeat distances of DPPC multilamellar membranes. This fact is indicative of dehydration of the intermembrane space and a steric contact between adjacent DPPC bilayers at 15% mole fraction of DMSO.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. M. A. Kiselev, Phys. Part. Nucl. 42 (2), 302 (2011).

    Article  Google Scholar 

  2. J. F. Nagle and S. Tristram-Nagle, Biochim. Biophys. Acta 1469, 159 (2000).

    Article  Google Scholar 

  3. M. A. Kiselev, P. Lesieur, A. M. Kisselev, et al., J. Appl. Phys. A 74, S1654 (2002).

    Article  Google Scholar 

  4. M. A. Kiselev, E. V. Zemlyanaya, V. K. Aswal, and R. H. H. Neubert, Eur. Biophys. J. 35 (6), 477 (2006).

    Article  Google Scholar 

  5. M. A. Kiselev, E. V. Zemlyanaya, E. I. Zhabitskaya, and V. L. Aksenov, Crystallogr. Rep. 60 (1), 143 (2015).

    Article  ADS  Google Scholar 

  6. E. V. Zemlyanaya, M. A. Kiselev, J. Zbytovska, et al., Crystallogr. Rep. 51 (Suppl 1), p. S22 (2006).

    Article  Google Scholar 

  7. E. V. Zemlyanaya, M. A. Kiselev, R. Noibert, et al., Poverkhnost, No. 11, 14 (2008).

    Google Scholar 

  8. M. A. Kiselev, E. V. Zemlyanaya, N. Y. Ryabova, et al., Appl. Phys. A 116, 319 (2014).

    Article  ADS  Google Scholar 

  9. N. Kucerka, N. Mu-Ping, and J. John Katsaras, Advances in Planar Lipid Bilayers and Liposomes (Academic, Burlington, 2010), Vol. 12, p. 201.

    Book  Google Scholar 

  10. M. A. Kiselev, P. Lesieur, A. M. Kisselev, et al., J. Alloys Compd. 286, 195 (1999).

    Article  Google Scholar 

  11. R. C. MacDonald, R. I. MacDonald, B. P. Menco, et al., Biochim. Biophys. Acta 1061, 297 (1991).

    Article  Google Scholar 

  12. M. A. Kiselev, D. Lombardo, A. M. Kiselev, et al., Poverkhnost, No. 11, 20 (2003).

    Google Scholar 

  13. H. Schmiedel, P. Joerchel, M. Kiselev, and G. Klose, J. Phys. Chem. B 105, 111 (2001).

    Article  Google Scholar 

  14. D. I. Svergun and L. A. Feigin, X-Ray and Small-Angle Neutron Scattering (Nauka, Moscow, 1986) [in Russian].

    Google Scholar 

  15. J. S. Pedersen, D. Posselt, and K. Mortensen, J. Appl. Crystallogr. 23, 321 (1990).

    Article  Google Scholar 

  16. Y. M. Ostanevich, Makromol. Chem. Macromol. Symp. 15, 91 (1988).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Joint Institute for Nuclear Research, Dubna, Moscow region, 141980, Russia

    M. A. Kiselev & E. V. Zemlyanaya

Authors
  1. M. A. Kiselev
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. V. Zemlyanaya
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. A. Kiselev.

Additional information

Original Russian Text © M.A. Kiselev, E.V. Zemlyanaya, 2017, published in Kristallografiya, 2017, Vol. 62, No. 5, pp. 795–799.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kiselev, M.A., Zemlyanaya, E.V. Dimethyl sulfoxide-induced dehydration of the intermembrane space of dipalmitoylphosphatidylcholine multilamellar vesicles: Neutron and synchrotron diffraction study. Crystallogr. Rep. 62, 763–767 (2017). https://doi.org/10.1134/S106377451705011X

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S106377451705011X

Search

Navigation