Skip to main content
Log in

Phase dispersion X-ray imaging of murine soft tissue

  • Structure of Macromolecular Compounds
  • Published:
Crystallography Reports Aims and scope Submit manuscript

Abstract

The generation of phase-contrast (PC) images in the phase-dispersion introscopy (PDI) technique is the subject of this paper. Conditions for extreme sensitivity to murine soft-tissue anatomy are discussed. The unique information content and good contrast of the minutest details of anatomy, together with the high brilliance of X-ray optics, give the authors confidence that the PDI method can be successfully applied for medical diagnostics.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. V. N. Ingal and E. A. Beliaevskaya, J. Phys. D: Appl. Phys. 28, 2314 (1995).

    Article  ADS  Google Scholar 

  2. T. V. Yushkevich, V. N. Ingal, and E. A. Beliaevskaya, Morphology 114(5), 51 (1998).

    Google Scholar 

  3. M. J. Kitchen, R. A. Lewis, N. Yagi, et. al., Br. J. Radiol. 78, 1018 (2005).

    Article  Google Scholar 

  4. S. W. Wilkins, T. E. Gureyev, D. Gao, et. al., Nature 384, 335 (1996).

    Article  ADS  Google Scholar 

  5. F. Pfeiffer, T. Weitkamp, O. Bunk, et al., Nature Phys. 2, 258 (2006).

    Article  ADS  Google Scholar 

  6. C. Kottler, F. Pfeiffer, O. Bunk, et. al., Phys. Status Solidi A 204 (2007).

  7. M. Bech, T. H. Jensen, R. Feidenhans, et al., Phys. Med. Biol. 54, 2747 (2009).

    Article  Google Scholar 

  8. R. A. Lewis, C. J. Hall, A. P. Hufton, et. al., J. Radiol. 76, 301 (2003).

    Google Scholar 

  9. I. Nesch, D. P. Fogarty, T. Tzvetkov, et. al., Rev. Sci. Instum. 80, 093702 (2009).

    Article  ADS  Google Scholar 

  10. A. Momose, Optics Express 11(19), 2303 (2003).

    Article  ADS  Google Scholar 

  11. M. Hoshino, K. Uesugi, and N. Yagi, Biol. Open 1, 269 (2012).

    Article  Google Scholar 

  12. E. D. Pisano, R. E. Johnston, D. Chapman, et al., Radiology 214, 895 (2000).

    Article  Google Scholar 

  13. S. Fiedler, A. Bravin, J. Keyriläinen, et. al., Phys. Med. Biol. 49, 175 (2004).

    Article  Google Scholar 

  14. C. Parham, Z. Zong, D. M. Connor, et. al., Acad. Radiol. 16, 911 (2009).

    Article  Google Scholar 

  15. L. Faulconer, C. Parham, D. M. Connor, et al., Acad. Radiol. 16(11), 1329 (2009).

    Article  Google Scholar 

  16. E. Castelly, M. Tonutti, F. Arfelly, et. al., Radiology. 259(3), 684 (2011).

    Article  Google Scholar 

  17. D. Stutman, T. J. Beck, J. A. Carrino, et al., Phys. Med. Biol. 56, 5697 (2011).

    Article  Google Scholar 

  18. V. N. Ingal, E. A. Beliaevskaya, A. P. Brianskaya, et. al., Phys. Med. Biol. 43, 2555 (1998).

    Article  Google Scholar 

  19. S. C. Mayo, T. J. Davis, T. E. Gureyev, et. al., Optics Express 11(19), 2292.

  20. T. Tanaka, C. Honda, S. Matsuo, et al., Invest. Radiol. 40, 385 (2005).

    Article  Google Scholar 

  21. M. Engelhardt, J. Baumann, M. Schuster, et. al., Appl. Phys. Lett. 90, 224101 (2007).

    Article  ADS  Google Scholar 

  22. C. J. Kotre, I. P. Birch, and K. J. Robson, Br. J. Radiol. 75, 170 (2002).

    Google Scholar 

  23. A. Olivo, K. Ignatyev, P. R. T. Murno, et. al., Nucl. Instrum. Methods Phys. Res., Sect. A 648, S28 (2011).

    Article  ADS  Google Scholar 

  24. V. A. Somenkov, A. K. Tkalich, and S. Sh. Shilstein, Sov. Tech. Phys. 61(11), 1309 (1991).

    Google Scholar 

  25. E. A. Beliaevkaya, M. Gambaccini, V. N. Ingal, et. al., Phys. Medica XIV(1), 19 (1998).

    Google Scholar 

  26. V. N. Ingal, E. A. Beliaevskaya, and V. P. Efanov, RF Patent No. 2012872. G01 N 23/02 (May 14, 1991); V. N. Ingal, E. A. Beliaevskaya, and V. P. Efanov, US Patent No. 5,319,694 (June 7, 1994).

  27. V. A. Bushuev, V. N. Ingal, and E. A. Beliaevskaya, Crystallogr. Rep. 43, 586 (1998).

    Google Scholar 

  28. V. A. Bushuev, V. N. Ingal, and E. A. Beliaevskaya, Crystallogr. Rep. 41, 808 (1996).

    Google Scholar 

  29. V. N. Ingal and E. A. Beliaevskaya, J. Tech. Phys. 63(6), 137 (1993).

    Google Scholar 

  30. P. Popesko, Color Atlas of the Anatomy of Small Laboratory Animals: Rat, Mouse, Golden Hamster (Wolfe, London, 1992).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to V. N. Ingal.

Additional information

The article was translated by the authors.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ingal, V.N., Ingal, E.A. Phase dispersion X-ray imaging of murine soft tissue. Crystallogr. Rep. 58, 1002–1009 (2013). https://doi.org/10.1134/S1063774513070092

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1063774513070092

Keywords

Navigation