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Wound healing potential of chitosan and N-sulfosuccinoyl chitosan derivatives

  • Developmental Biology
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Abstract

Comparative study of chitosan wound healing properties and its synthesized derivatives in MC-100 gel was carried out using the model of experimental full thickness skin wounds. It was determined that N-sulfosuccinoyl chitosan derivatives added into the gel in a concentration of 0.05% possess the higher wound healing activity in comparison with other chitosan derivatives and decrease the half-healing period of wounds 2–3 times in comparison with the control.

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Authors and Affiliations

  1. Institute of Energy Problems of Chemical Physics, Russian Academy of Science, Leninskii pr. 38/2, Moscow, 119334, Russia

    T. P. Alekseeva, O. A. Bogoslovskaya, I. P. Olkhovskaya & N. N. Glushchenko

  2. Peoples’ Friendship University of Russia, Miklukho-Maklaya 6, Moscow, 117198, Russia

    A. A. Rakhmetova

  3. Center Bioinzeneria, Russian Academy of Science, pr. 60 let Oktyabrya 7/1, Moscow, 117312, Russia

    A. V. Il’ina & V. P. Varlamov

  4. Familiprix Lasalle, rue Airlie, Lasalle, Montreal-Ouest, 9316, Canada

    T. A. Baitukalov

Authors
  1. T. P. Alekseeva
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  2. A. A. Rakhmetova
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  3. O. A. Bogoslovskaya
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  4. I. P. Olkhovskaya
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  5. A. N. Levov
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  6. A. V. Il’ina
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  7. V. P. Varlamov
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  8. T. A. Baitukalov
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  9. N. N. Glushchenko
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Corresponding author

Correspondence to N. N. Glushchenko.

Additional information

Original Russian Text © T.P. Alekseeva, A.A. Rakhmetova, O.A. Bogoslovskaya, I.P. Olkhovskaya, A.N. Levov, A.V. Il’ina, V.P. Varlamov, T.A. Baitukalov, N.N. Glushchenko, 2010, published in Izvestiya Akademii Nauk, Seriya Biologicheskaya, 2010, No. 4, pp. 403–410.

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Alekseeva, T.P., Rakhmetova, A.A., Bogoslovskaya, O.A. et al. Wound healing potential of chitosan and N-sulfosuccinoyl chitosan derivatives. Biol Bull Russ Acad Sci 37, 339–345 (2010). https://doi.org/10.1134/S1062359010040023

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  • DOI: https://doi.org/10.1134/S1062359010040023

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