Journal of Analytical Chemistry

, Volume 65, Issue 2, pp 174–182 | Cite as

Gas-chromatographic determination of O-isobutyl-S-2-(N,N-diethylamino)ethyl methylphosphonothioate (VX-like compound) and O-isopropyl methylphosphonofluoridate (Sarin) traces in slag

  • I. N. Stans’kov
  • V. B. Kondrats’ev
  • E. N. Glukhan
  • V. I. Tsekhmister
  • S. V. Sadovnikov
  • A. P. Suchkov
  • I. D. Derevyagina
Articles

Abstract

Procedures for the determination of 04sobutyl- S-2-(N,N-diethylamino)ethyl methylphosphonothioate (VX-like compound) and sarin traces in slag at levels of 5 × 10-5 and 1 × 10-2 mg/kg, respectively, were developed. The procedures are based on the extraction of organophosphorus chemical warfare agents from slag, the preconcentration of the extract, and the conversion of the analytes into dialkyl methylphos-phonates with the use of optically active alcohols. In this case, a solution of AgNO3 in 4-methyl-2-pentanol or a sodium alcoholate solution was used for the derivatization of VX or sarin, respectively. The resulting dias-tereomers were determined by gas chromatography with the use of a flame-photometric detector. The analysis time was no longer than 1.2 or 1 h for the VX-like compound or sarin, respectively.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    GOST (State Standard) 12.1.007-76: Occupational Safety Standards System. Harmful Substances. Classification and Safety, Moscow, 1978.Google Scholar
  2. 2.
    Stans’kov, I.N., Kondrats’ev, V.B., Tsekhmister, V.I., Sadovnikov, S.V., Derevyagina, I.D., and Morozova, O.T., Zhurn. fizich. khim., 2008 [Russ. J. Phys. Chem. (Engl. Transl.), 2008], (in press).Google Scholar
  3. 3.
    Allenmark, S.G., Chromatographic Enantioseparation: Methods and Applications, Chichester: Horwood, 1998.Google Scholar
  4. 4.
    Zenkevich, I.G., in Encyclopedia of Chromatography, Cazes, J., Ed., New York: Marsel Dekker, 2001, p. 228.Google Scholar
  5. 5.
    Gnedenko, B.V., Kurs teorii veroyatnostei (A Theory of Probability), Moscow: Nauka, 1961.Google Scholar
  6. 6.
    Tals’roze, V.L., Raznikov, V.V., and Tantsyrev, G.D., Dokl. Akad. Nauk SSSR, 1964, vol. 159, no. 1, p. 182.Google Scholar
  7. 7.
    Stans’kov, I.N., Sergeeva, A.A., and Sitnikov, V.B., Zhurn. anal. khim., 2007, vol. 62, no. 6, p. 628 [J. Anal. Chem. (Engl. Transl.), vol. 62, no. 6, p. 564].Google Scholar
  8. 8.
    Stans’kov, I.N., Sergeeva, A.A., Sitnikov, V.B., Derevyagina, I.D., and Morozova, O.T., Zhurn. anal. khim., 2004, vol. 59, no. 11, p. 1194 [J. Anal. Chem. (Engl. Transl.), vol. 59, no. 11, p. 1081].Google Scholar
  9. 9.
    Stans’kov, I.N., Sergeeva, A.A., and Derevyagina, I.D., Zhurn. anal. khim., 2003, vol. 58, no. 2, p. 182 [J. Anal. Chem. (Engl. Transl.), vol. 58, no. 2, p. 160].Google Scholar
  10. 10.
    Franke, S., Frank, P., and Warnke, W., Lehrbuch der Militárchemie (Manual of Military Chemistry), Berlin: Deut. Militárverlag, 1969, vol. 2.Google Scholar

Copyright information

© Pleiades Publishing, Ltd. 2010

Authors and Affiliations

  • I. N. Stans’kov
    • 1
  • V. B. Kondrats’ev
    • 1
  • E. N. Glukhan
    • 1
  • V. I. Tsekhmister
    • 1
  • S. V. Sadovnikov
    • 1
  • A. P. Suchkov
    • 1
  • I. D. Derevyagina
    • 1
  1. 1.Russian Research Institute of Organic Chemistry and TechnologyMoscowRussia

Personalised recommendations