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Surface Modification of Glassy Carbon Electrode Using Hematoxylin and MWCNTs/Fe3O4/TiO2 Nanocomposite; a Sensitive Electrochemical Technique for Detection of Methyldopa in the Presence of Folic Acid

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Abstract

A sensitive electrochemical sensor was developed by modifying a glassy carbon electrode (GCE) with hematoxylin and MWCNTs/Fe3O4/TiO2 nanocomposite for the improved detection of methyldopa in the presence of folic acid. Electrochemical methods such as cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CHA) were used to describe the electrochemical performance of the hematoxylin–MWCNTs/Fe3O4/TiO2/GCE for methyldopa and folic acid sensing studies. Methyldopa and folic acid were detected by DPV method at 190  and 720 mV, respectively. Due to the synergistic effect of the hematoxylin and MWCNTs/Fe3O4/TiO2 nanocomposite, the modified electrode exhibited good sensing performance to methyldopa and folic acid in the range of 0.5–300  μM with detection limit of 0.02 μM. Also, this method was applied for the quantification of methyldopa and folic acid in real samples.

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  1. Department of Chemistry, Bandar Abbas Branch, Islamic Azad University, Bandar Abbas, Iran

    Sakineh Esfandiari Baghbamidi

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Sakineh Esfandiari Baghbamidi Surface Modification of Glassy Carbon Electrode Using Hematoxylin and MWCNTs/Fe3O4/TiO2 Nanocomposite; a Sensitive Electrochemical Technique for Detection of Methyldopa in the Presence of Folic Acid. Russ J Electrochem 58, 451–463 (2022). https://doi.org/10.1134/S1023193522060040

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