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The Increase in Electrical Conductivity and the Appearance of Lipid Pores Induced by Magnetic Nanoparticles CoFe2O4 in Bilayer Lipid Membranes

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Abstract

The electrical conductivity of azolectine bilayer lipid membranes is observed to increase 10–40-fold with respect to its background value of 67 ± 13 pS/mm2 upon the addition of cubic CoFe2O4 nanoparticles with the main diagonal of 14 nm (MNP-14) and 27 nm (MNP-27). As the concentration of MNP-14 in the membrane solution increases from 50 to 450 µg/mL, the increase in the membrane conductivity with respect to its background value is nonlinear and can be approximated by the exponential dependence with exponent 2.75. Discrete current pulses are observed in the constant voltage mode for the MNP-14 concentration higher than 250 µg/mL and for all MNP-27 concentrations starting from 50 µg/mL, which points to the appearance of conducting lipid pores.

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Funding

This study was carried out within the framework of problems elaborated at the Institute of Problems of Chemical Physics of the Russian Academy of Sciences (АААА-А19-119092390079-8) and also at the Institute of Radio-engineering and Electronics of the Russian Academy of Sciences (AAAA-A19-119041590070-1). The study was supported by the grant of the President of RF for Leading Scientific Schools 2644.2020.2.

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Authors and Affiliations

  1. Sechenov First Moscow State Medical University, 119991, Moscow, Russia

    A. A. Anosov, O. V. Koplak, A. S. Derunets & R. B. Morgunov

  2. Kotelnikov Institute of Radio-engineering and Electronics, Russian Academy of Science, 125009, Moscow, Russia

    A. A. Anosov

  3. Pirogov Russian National Research Medical University, 117997, Moscow, Russia

    E. A. Korepanova

  4. Institute of Problems of Chemical Physics, Russian Academy of Science, 142432, Chernogolovka, Moscow oblast, Russia

    O. V. Koplak & R. B. Morgunov

  5. MIREA—Russian Technological University, 119991, Moscow, Russia

    V. A. Kazamanov

Authors
  1. A. A. Anosov
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  2. E. A. Korepanova
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  3. O. V. Koplak
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  4. V. A. Kazamanov
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  5. A. S. Derunets
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  6. R. B. Morgunov
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Correspondence to A. S. Derunets.

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Translated by T. Safonova

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Anosov, A.A., Korepanova, E.A., Koplak, O.V. et al. The Increase in Electrical Conductivity and the Appearance of Lipid Pores Induced by Magnetic Nanoparticles CoFe2O4 in Bilayer Lipid Membranes. Russ J Electrochem 58, 321–328 (2022). https://doi.org/10.1134/S102319352203003X

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  • DOI: https://doi.org/10.1134/S102319352203003X

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