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Analysis of peanut gene RNAi in drosophila oogenesis

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Abstract

The peanut gene functions in Drosophila melanogaster oogenesis were studied. It was demonstrated that the suppression of peanut expression by RNA interference in follicle cells led to oocyte polarization defects, anomalous cytokinesis in the chorion cells, and aberrant chromatin condensation in follicle cells. No oogenesis abnormalities were observed in females with decreased peanut gene expression in ovarian germline cells. However, embryos produced by such females had a decreased survival rate caused by two peaks of embryonic death.

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Authors and Affiliations

  1. Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, pr. Lavrent’eva 10, Novosibirsk, 630090, Russia

    K. A. Akhmetova, N. V. Dorogova & S. A. Fedorova

  2. University of Alabama at Birmingham, 552 Kaul Building, 720 20th Street South, Birmingham, AL, 35294, United States

    K. A. Akhmetova & I. N. Chesnokov

  3. Novosibirsk State University, Novosibirsk, 630090, Russia

    K. A. Akhmetova & S. A. Fedorova

Authors
  1. K. A. Akhmetova
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  2. N. V. Dorogova
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  3. I. N. Chesnokov
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  4. S. A. Fedorova
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Corresponding author

Correspondence to K. A. Akhmetova.

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Original Russian Text © K.A. Akhmetova, N.V. Dorogova, I.N. Chesnokov, S.A. Fedorova, 2015, published in Genetika, 2015, Vol. 51, No. 9, pp. 991–999.

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Akhmetova, K.A., Dorogova, N.V., Chesnokov, I.N. et al. Analysis of peanut gene RNAi in drosophila oogenesis. Russ J Genet 51, 847–854 (2015). https://doi.org/10.1134/S1022795415090021

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  • DOI: https://doi.org/10.1134/S1022795415090021

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