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Histone modification and regulation of chromatin function

  • Theoretical Papers and Reviews
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Abstract

Nucleosomes play two main roles, acting as basal units in DNA compaction and coordinating most processes in chromosomes. The coordination is due to modification of histones, proteins forming nucleosomes. The review briefly describes the nucleosome structure and major modifications of histones and considers the role of such modifications in transcriptional suppression and activation.

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Authors and Affiliations

  1. Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, 630090, Russia

    D. E. Koryakov

  2. Department of Cytology and Genetics, Novosibirsk State University, Novosibirsk, 630090, Russia

    D. E. Koryakov

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Original Russian Text © D.E. Koryakov, 2006, published in Genetika, 2006, Vol. 42, No. 9, pp. 1170–1185.

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Koryakov, D.E. Histone modification and regulation of chromatin function. Russ J Genet 42, 970–984 (2006). https://doi.org/10.1134/S1022795406090043

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  • DOI: https://doi.org/10.1134/S1022795406090043

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