References
Pharmaceutical Market Trends, 2008–2012 (URCH, 2008).
S. I. Gavrilova, “Pharmacotherapy of Alzheimer’s: AMyth or a Reality?” in Proc. of the 2nd Russian Conf. “Alzheimer’s Disease and Aging: From Neurobiology to Therapy” (Pul’s, Moscow, 1999), pp. 25–44 [in Russian].
V. A. Palyulin, E. V. Radchenko, and N. S. Zefirov, “Molecular Field Topology Analysis Method in QSAR Studies of Organic Compounds,” J. Chem. Inf. Comput. Sci. 40, 659 (2000).
N. M. Halberstam, I. M. Baskin, V. A. Palyulin, and P. S. Zefirov, “Neural Networks as a Method for Elucidating Structure-Property Relationships for Organic Compounds,” Usp. Khim. 72, 706 (2003) [Russ. Chem. Rev. 72, 629 (2003)].
I. I. Baskin, I. G. Tikhonova, V. A. Palyulin, and N. S. Zefirov, “Selectivity Fields: Comparative Molecular Field Analysis (CoMFA) of the Glycine/NMDA and AMPA Receptors,” J. Med. Chem. 46, 4063 (2003).
C. G. Parsons et al., “Memantine: An NMDA Receptor Antagonist That Improves Memory by Restoration of Homeostasis in the Glutamatergic System—Too Little Activation Is Bad, Too Much Is Even Worse,” Neuropharmacology 53, 699 (2007).
M. J. O’Neill and S. Dix, “AMPA Receptor Potentiators as Cognitive Enhancers,” Drugs 10, 185 (2007).
R. P. Sheridan, “The Most Common Chemical Replacements in Drug-Like Compounds,” J. Chem. Inf. Comput. Sci. 42, 103 (2002).
RF Patent No. 2223952 (2004).
S. Bachurin, E. Bukatina, N. Lermontova, et al., “Antihistamine Agent Dimebon as Novel Neuroprotector and Cognition Enhancer,” Ann. New York Acad. Sci. 939, 425 (2001).
S. Doody, S. I. Gavrilova, M. Sano, et al., “Dimebon Improves Cognition, Behavior, Activities of Daily Living, and Global Function in a Randomised, Double-Blind, Placebo-Controlled 6-Month Study of Patients with Mild-to-Moderate Alzheimer’s Disease,” Lancet 372, 207 (2008).
A. Pollak, “Antihistamine Shows Promise in Treating Alzheimer’s,” The New York Times, June 11 (2007).
Additional information
Original Russian Text © S.O. Bachurin, N.S. Zefirov, 2010, published in Vestnik Rossiiskoi Akademii Nauk, 2010, Vol. 80, No. 5–6, pp. 497–503.
Rights and permissions
About this article
Cite this article
Bachurin, S.O., Zefirov, N.S. Medical chemistry for brain function correction. Her. Russ. Acad. Sci. 80, 279–284 (2010). https://doi.org/10.1134/S1019331610030147
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1019331610030147