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Effect of Motion Trajectory on the Lateralization of Auditory Evoked Responses

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Abstract

Processing of acoustic space in the human auditory system implicates the interaction of the left and right hemispheres of the brain. In this study, we investigated the influence of the position and motion direction of sound stimuli on the amplitude and latency of N1, P2, MMN, and P3a components of auditory evoked potentials in the left and right brain hemispheres. The data suggest that functional asymmetry of the N1P2 complex and difference waveforms can be described as weak contralateral dominance. Deviants moving from the lateral positions evoked later P3a components than those moving from the midline, which is consistent with the concept of higher localization accuracy in the frontal part of the acoustic space. The motion direction affected the MMN and P3a latency: the centrifugal deviants produced earlier MMN and P3a responses than the centripetal deviants. This could result from a stronger orienting reaction caused by stimuli moving from the center towards the periphery as compared with the opposite direction.

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Funding

This study was supported by the Basic Research Program for State Academies for 2013–2020 (GP-14, section 63.3).

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Authors and Affiliations

  1. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia

    E. A. Petropavlovskaia & L. B. Shestopalova

  2. St. Petersburg State University, St. Petersburg, Russia

    L. A. Kanakhina

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  1. E. A. Petropavlovskaia
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Correspondence to E. A. Petropavlovskaia.

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Statement of compliance with standards of research involving humans as subjects. All studies were conducted in accordance with the principles of biomedical ethics set out in the 1964 Helsinki Declaration and its subsequent amendments and approved by the Ethics Committee of the St. Petersburg State University (Saint-Petersburg). Each study participant provided a voluntary written informed consent signed after explanations of potential risks and benefits as well as the nature of the forthcoming investigations.

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Translated by M. Batrukova

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Petropavlovskaia, E.A., Kanakhina, L.A. & Shestopalova, L.B. Effect of Motion Trajectory on the Lateralization of Auditory Evoked Responses. Hum Physiol 46, 351–365 (2020). https://doi.org/10.1134/S0362119720020127

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