Abstract
This paper reports changes in the main parameters of lower limb veins in 35 cosmonauts in the course of six-month space missions. Major reduction in the leg volume was shown in all cosmonauts, as well as a significant increase in venous capacitance and compliance. The rate of lower leg vein filling exhibited different trends; it was decreased in the majority of cosmonauts (n = 26, 74%) and increased in the rest (n = 9, 26%). Increases in venous capacitance, compliance, and filling rates may impact orthostatic stability (OS). These changes are among the pathophysiological mechanisms of the OS loss in spaceflight.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Grandpierre, R., Colleu, M., Hauttement, J.L., et al., Intérêt et movens d’étude de la circulation sanguine périphérique an apesanteur, Proc. IV Int. Symp. “Human in Space,” Yerevan, 1971, Moscow, 1974, pp. 125–141.
Shik, L.L., Sergeeva, K.A., and Moiseev, V.A., Investigation of reasons of orthostatic instability, in Problemy kosmicheskoi biologii (Problems of Space Biology), Moscow: Nauka, 1975, vol. 31, pp. 157–164.
Khayutin, V.M., Shenderov, S.M., Zakharov, A.G., and Rogoza, A.N., Orthostatic instability of blood circulation system: the role of resistive vessels detraining, Kosm. Biol. Aviakosm. Med., 1984, vol. 18, no. 4, pp. 4–12.
Buckey, J.C., Lane, L.D., Levine, B.D., et al., Orthostatic intolerance after spaceflight, J. Appl. Physiol., 1996, vol. 81, no. 1, pp. 7–18.
Bungo, H.W., The cardiopulmonary system, in Space Physiology and Medicine, Nicogossian, A.E., Leach-Huntoon, C., and Pool, S.L., Eds., Philadelphia: Lea and Febiger, 1989, pp. 179–201.
Tyberg, J.V. and Hamilton, V.R., Orthostatic hypotension and the role of changes in venous capacitance, Med. Sci. Sport Exerc., 1996, vol. 28, pp. 29–32.
Fomina, G.A., Kotovskaya, A.R., Talavrinov, V.A., et al., Condition of the lower limb veins of in the shortand long-term space flights (according to occlusive plethysmography data), in Orbital’naya stantsiya “Mir” (Mir Orbital Station), Moscow: Inst. Med.-Biol. Probl., Ross. Akad. Nauk, 2002, vol. 2, chap. 8, pp. 510–519.
Kotovskaya, A.R., Fomina, G.A., Salnikov, A.V., and Yarmanova, E.N., Development of methodology for the study of the lower limbs veins of cosmonauts as regards to the practice of space medicine, Aviakosm. Ekol. Med., 2014, vol. 48, no. 6, pp. 5–9.
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © A.R. Kotovskaya, G.A. Fomina, A.V. Salnikov, 2015, published in Aviakosmicheskaya i Ekologicheskaya Meditsina, 2015, Vol. 49, No. 5, pp. 5–10.
Rights and permissions
About this article
Cite this article
Kotovskaya, A.R., Fomina, G.A. & Salnikov, A.V. Variation of the State of Lower Limb Veins in Cosmonauts during Long-term Missions. Hum Physiol 43, 769–773 (2017). https://doi.org/10.1134/S036211971707009X
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S036211971707009X