Effect of audible sound in form of music on microbial growth and production of certain important metabolites
- 893 Downloads
Effect of a type of Indian classical music (Raag Kirwani) comprised of the sound corresponding to a frequency range of 38–689 Hz, on microbial growth, production of certain important metabolites, and antibiotic susceptibility was investigated. All the bacteria and yeasts used as test organisms were found to register better (3.15–40.37% higher) growth under the influence of music, except Serratia marcescens. Music treatment was also found to affect production of bacterial pigments (prodigiosin and violacein) whose production is normally linked with quorum-sensing in the producing bacteria. All the test organisms exhibited an increased antibiotic susceptibility (increase ranging from 3.81–18.69%) under the influence of music. Chromobacterium violaceum and S. marcescens were found to degrade cephazolin at a faster rate when incubated with music. Membrane permeability of the test organisms seemed to get altered owing to music treatment. Intracellular concentration of cations (calcium and potassium) and protein content of the music treated cultures was also significantly different than the untreated control. The audible sound in form of music employed in this study was able to affect growth, metabolism, and antibiotic susceptibility of prokaryotic as well as eukaryotic microbes.
Keywordssound music membrane permeability growth calcium pottasium antibiotic susceptibility
Unable to display preview. Download preview PDF.
- 1.Butler, M., Cells and sound: an introduction, Physical Biology Articles. http://www.academia.edu/1285421/Cells_and_sound_an_introduction_Review_to_be_submitted_2013
- 3.Ying, J.C.., Dayou, J., and Phin, C.K., Experimental investigation on the effects of audible sound to the growth of Escherichia coli, Modern Appl. Sci., 2009, vol. 3, no. 3, p. 124.Google Scholar
- 9.Pradeep, B.V., Pradeep, F.., Angayarkanni, J., and Palaniswamy, M., Optimization and production of prodigiosin from Serratia marcescens MBB05 using various natural substrates, Asian J. Pharm. Clin. Res., 2013, vol. 6, no. 1.Google Scholar
- 12.Harley, J.P., and Prescott L.M., Laboratory Exercises in Microbiology, 5th ed., McGraw Hill, 2000.Google Scholar
- 14.Kaneko, T., Matsuhashi, M., and Otani, S., U.S. Patent 5,955,334, 1999.Google Scholar
- 15.Yoshimura, M. et al., “Sound wave” signals, emitted by bacteria and yeast cells, regulate the propagation of yeast under alcohol stress, Japan Soc. Biosci., Biotechnol. Agrochem., Aug. 1, 1995, Conference Abstracts.Google Scholar
- 16.Pornpongmetta, S. and Thanuttamavong, M., Effects of music on microbial substrate utilization of aerobic bacteria from municipal wastewater treatment plant part II: Comparative effects of musical characteristics, 2010. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394891/ Google Scholar
- 24.Norris, V. and Hyland, G.J., Do bacteria sing? Sonic intercellular communication between bacteria may reflect electromagnetic intracellular communication involving coherent collective vibrational modes that could integrate enzyme activities and gene expression, Mol. Microbiol., 1997, vol. 24, no. 4, pp. 879–880.CrossRefPubMedGoogle Scholar