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SYNTHESIS, CRYSTAL STRUCTURES, AND UREASE INHIBITORY ACTIVITY OF SCHIFF BASE COPPER AND NICKEL COMPLEXES

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Abstract

Urease inhibitors can inhibit the decomposition rate of urea, and decrease the air pollution caused by ammonia. In this paper, three new copper(II) and nickel(II) complexes [Cu2L2(μ1,1-N3)2] (1), [Cu(HL)2]Br2 (2), and [Ni3L2(DMF)2(μ2–η1:η1-CH3COO)2(μ1,1-N3)2] (3), where L = 5-bromo-2-(((2-isopropylamino) ethyl)imino)methyl)phenolate, HL = 5-bromo-2-(((2-isopropylammonio)ethyl)imino)methyl)phenolate are synthesized and characterized. The complexes are characterized by elemental analyses, IR, UV-Vis spectra, molar conductivity, and single crystal X-ray diffraction. The X-ray analysis indicates that Cu atoms in complexes 1 and 2 are in square pyramidal and square planar coordination, respectively. The Ni atoms in complex 3 are in octahedral coordination. The molecules of the complexes are linked through hydrogen bonds and π⋯π interactions. The inhibitory effects of the complexes on jack bean urease are studied, which show that the copper complexes have a strong inhibitory effect on urease.

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  1. Heilongjiang Province Qiqihar Ecological Environment Monitoring Center, Qiqihar, People’s Republic of China

    Y. Wang

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Russian Text © The Author(s), 2021, published in Zhurnal Strukturnoi Khimii, 2021, Vol. 62, No. 11, pp. 1780-1790.https://doi.org/10.26902/JSC_id81674

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Wang, Y. SYNTHESIS, CRYSTAL STRUCTURES, AND UREASE INHIBITORY ACTIVITY OF SCHIFF BASE COPPER AND NICKEL COMPLEXES. J Struct Chem 62, 1667–1677 (2021). https://doi.org/10.1134/S0022476621110020

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