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Thyroid hormones in the skeletogenesis and accessory sources of endogenous hormones in Xenopus laevis (Amphibia; Anura) ontogeny: Experimental evidence

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Abstract

Skeletal development was studied in normal and goitrogen-treated Xenopus laevis tadpoles reared under thyroid hormone (TH) deficiency. Early stages of skeletal development proceed similarly in both groups. Later stages are retarded or completely arrested in goitrogen-treated tadpoles. After goitrogen-treated tadpoles were transferred into pure water or into a medium containing both goitrogen and exogenous TH, tadpoles resumed development. Consequently, late stages of skeletogenesis are TH-dependent and TH-induced. Athyroid X. laevis “giant tadpoles” described in literature differ from goitrogen-arrested tadpoles in that they have features which require TH to appear. The appearance of TH-depended features in giant tadpoles indicates the occurrence of the additional sources of TH other than thyroid gland.

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References

  1. Schreiber, A.M., Das, B., Huang, H., Marsh-Armstrong, N., and Brown, D.D., Proc. Natl. Acad. Sci. USA, 2001, vol. 98, pp.10739–10744.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Brown, D.D. and Cai, L., Dev. Biol., 2007, vol. 306, pp.20–33.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  3. Schlosser, G., Koyano-Nakagawa, N., and Kintner, C., Dev. Dyn., 2002, vol. 225, pp.485–498.

    Article  CAS  PubMed  Google Scholar 

  4. Wangh, L.J. and Schneider, W., Dev. Biol., 1982, vol. 89, pp.287–293.

    Article  CAS  PubMed  Google Scholar 

  5. Brown, D.D. Cai, L., Das, B., Marsh-Armstrong, N., Schreiber, A.M., and Juste, R., Proc. Nat. Acad. Sci. USA, 2005, vol. 102, pp.12455–12458.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  6. Schreiber, A.M. and Brown, D.D., Proc. Nat. Acad. Sci. USA, 2003, vol. 100, pp.1769–1774.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  7. Kerney, R., Wassersug, R., and Hall, B.K., J. Anat., 2010, vol. 216, pp.132–143.

    Article  PubMed Central  PubMed  Google Scholar 

  8. Nieuwkoop, P.D. and Faber, J., Normal Table of Xenopus Laevis (Daudin): A Systematical and Chronological Survey of the Development from the Fertilized Egg till the End of Metamorphosis, Amsterdam: North-Holland, 1956.

    Google Scholar 

  9. Morvan, Dubois, G., Sebillot, A., Kuiper, G.G.J.M., Verhoelst, C.H.J., Darras, V.M., Visser, T.J., and Demeneix, B.A., Endocrinology, 2006, vol. 147, pp.4941–4949.

    Article  Google Scholar 

  10. Rot-Nikcevic, I. and Wassersug, R.J., J. Exp. Biol., 2004, vol. 207, pp.2133–2145.

    Article  PubMed  Google Scholar 

  11. Gancedo, B., Alonso-Gomez, A.L., de Pedro, N., Delgado, M.J., and Alonso-Bedate, M., Gen. Comp. Endocrinol., 1997, vol. 107, pp.240–250.

    Article  CAS  PubMed  Google Scholar 

  12. Baker, K.F., J. Morphol., 1958, vol. 103, pp.91–129.

    Article  Google Scholar 

  13. Geven, E.J.W., Nha-Khanh Nguen, van den Boogaart M., Tom Spanings, F.A., Flik G., and Klaren, P.H.M., J. Exp. Biol., 2007, vol. 210, pp.4005–4015.

    Article  PubMed  Google Scholar 

  14. Gozzo, S., Taglioni, A., Casetti, R., Meloni, M., Bagnoli, C., and Monaco, V., Ital. J. Zool., 1996, vol. 63, pp.207–214.

    Article  Google Scholar 

  15. Gorbman, A., in Physiology of the Amphibia, New York: Academic, 1964, pp.371–410.

    Google Scholar 

Download references

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Authors and Affiliations

  1. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Leninskii pr. 33, Moscow, 119071, Russia

    S. V. Smirnov & A. B. Vassilieva

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  1. S. V. Smirnov
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  2. A. B. Vassilieva
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Correspondence to S. V. Smirnov.

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Original Russian Text © S.V. Smirnov, A.B. Vassilieva, 2014, published in Doklady Akademii Nauk, 2014, Vol. 455, No. 5, pp. 610–613.

The article was translated by the authors.

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Smirnov, S.V., Vassilieva, A.B. Thyroid hormones in the skeletogenesis and accessory sources of endogenous hormones in Xenopus laevis (Amphibia; Anura) ontogeny: Experimental evidence. Dokl Biol Sci 455, 136–138 (2014). https://doi.org/10.1134/S0012496614020185

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  • DOI: https://doi.org/10.1134/S0012496614020185

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