Abstract
This work focuses on the study of remote effects (duration of remission, recurrence rate, and average lifespan) in mice with Ehrlich ascites carcinoma exposed to oligofractionated irradiation with a pencil scanning beam of protons depending on the volume of the tissue being irradiated and the interval between dose fractions. The results show higher antitumor efficacy and a considerable increase in the average life span of mice after hypofractionated irradiation with a pencil scanning beam of protons at a total dose of 60 Gy of the gross tumor volume compared with the planning target volume.
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Original Russian Text © V.E. Balakin, A.E. Shemyakov, S.I. Zaichkina, O.M. Rozanova, E.N. Smirnova, S.P. Romanchenko, S.S. Sorokina, N.S. Strelnikova, 2017, published in Biofizika, 2017, Vol. 62, No. 1, pp. 161–167.
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Balakin, V.E., Shemyakov, A.E., Zaichkina, S.I. et al. The remote effects of radiation after hypofractionated irradiation with protons of Ehrlich ascites carcinoma in mice. BIOPHYSICS 62, 138–142 (2017). https://doi.org/10.1134/S0006350917010043
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DOI: https://doi.org/10.1134/S0006350917010043