Abstract
We studied the effect of taurine on renal function and the prooxidant–antioxidant balance in the kidneys and blood of rats under experimental rhabdomyolysis. It was found that taurine at a dose of 100 mg/kg of animal body weight improves renal function and normalizes prooxidant–antioxidant balance indicators, reducing the intensity of lipid and protein peroxidation and increasing catalase and glutathione peroxidase activities.
Similar content being viewed by others
References
V. M. Ermolenko and A. Yu. Nikolaev, Acute Renal Failure: A Manual *GEOTAR_Media, Moscow, 2010) [in Russian].
F.Y. Khan, Neth. J. Med. 67, 272 (2009).
I. I. Zamorskii and T. S. Shchudrova, Biophysics (Moscow) 59 (5), 834 (2014).
I. I. Zamorskii and V. G. Zeleniuk, Biophysics (Moscow) 59 (5), 837 (2014).
F. Lallemand and P. De Witte, Amino Acids 26, 111 (2004).
F. Li, I. G. Obrosova, and O. Abatar, Am. J. Physiol. Endocrinol. Metab. 288, 29 (2005).
C. Puerta, F. J. Arrieta, and J. I. Balsa, Nutr. Hosp. 25, 910 (2010).
L. D. Stal’naya and T. G. Garishvili, in Modern Methods in Biochemistry (Meditsina, Moscow, 1977), pp. 66–68 [in Russian].
M. A. Korolyuk, L. I. Ivanova, and I. G. Mayorova, Lab. Delo No. 1, 16 (1988).
I. F. Meshchishen and N. P. Grigor’eva, Buk. Med. Visn. 6 (2), 190 (2002).
V. G. Kolb and V. S. Kamyshnikov, A Handbook of Clinical Chemistry (Minsk, 1982) [in Russian].
I. F. Meshchishen, Buk. Med. Visn. 2 (1), 156 (1998).
A. K. Merzon, O. T. Titarenko, et al., Lab. Delo No. 7, 416 (1970).
A. I. Mikheeva and I. A. Bogodarova, Lab. Delo No. 7, 441 (1969).
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © I.I. Zamorskii, V.M. Drachuk, O.M. Goroshko, 2016, published in Biofizika, 2016, Vol. 5, No., pp. 1022–1025.
Rights and permissions
About this article
Cite this article
Zamorskii, I.I., Drachuk, V.M. & Goroshko, O.M. The nephroprotective effects of taurine in acute kidney injury due to rhabdomyolysis. BIOPHYSICS 61, 1036–1038 (2016). https://doi.org/10.1134/S0006350916050298
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S0006350916050298