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Renoprotective effects of statins under the conditions of acute renal failure, caused by rhabdomyolysis

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Abstract

The experiment on white rats was targeted at the examination of influence of statins (atorvastatin, lovastatin, simvastatin) under the conditions of acute renal failure, caused by rhabdomyolysis. Renoprotective effects of statins were demonstrated by reduction of hyperazotemia and proteinuria and improvement of renal excretory function, which correlated with antioxidant properties of drugs.

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Authors and Affiliations

  1. Bukovinian State Medical University, Chernivtsi, 58000, Ukraine

    I. I. Zamorskii & V. G. Zeleniuk

Authors
  1. I. I. Zamorskii
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  2. V. G. Zeleniuk
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Correspondence to I. I. Zamorskii.

Additional information

Original Russian Text © I.I. Zamorskii, V.G. Zeleniuk, 2014, published in Biofizika, 2014, Vol. 59, No. 5, pp. 1027–1030.

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Zamorskii, I.I., Zeleniuk, V.G. Renoprotective effects of statins under the conditions of acute renal failure, caused by rhabdomyolysis. BIOPHYSICS 59, 837–840 (2014). https://doi.org/10.1134/S0006350914050327

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  • DOI: https://doi.org/10.1134/S0006350914050327

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