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Changes in the physicochemical characteristics of rabbit sclera upon scleral reinforcement

  • Complex Systems Biophysics
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Abstract

Biochemical analysis and differential scanning calorimetry demonstrated that the connective tissue (capsule) formed around a reinforcing scleroplastic implant is similar to intact sclera, its main component being type I collagen organized in perfect fibrils with cross-linking sufficient for normal thermomechanical properties. DSC also revealed a fraction of collagen with heat-labile ‘immature’ cross-links around implants containing a stimulatory plant product Panaxel, which suggested high synthetic activity of fibroblasts.

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Authors and Affiliations

  1. Chemical Faculty, Moscow State University, Moscow, 119899, Russia

    N. Yu. Ignat’eva, S. V. Averkiev & V. V. Lunin

  2. Helmholtz Research Institute for Eye Diseases, Moscow, 105062, Russia

    E. N. Iomdina & Zh. N. Ivashchenko

  3. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, 119899, Russia

    L. A. Baratova & E. V. Lukashina

Authors
  1. N. Yu. Ignat’eva
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  2. S. V. Averkiev
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  3. E. N. Iomdina
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  4. Zh. N. Ivashchenko
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  5. L. A. Baratova
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  6. E. V. Lukashina
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  7. V. V. Lunin
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Original Russian Text © N.Yu. Ignat’eva, S.V. Averkiev, E.N. Iomdina, Zh.N. Ivashchenko, L.A. Baratova, E.V. Lukashina, V.V. Lunin, 2007, published in Biofizika, 2007, Vol. 52, No. 2, pp. 324–331.

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Ignat’eva, N.Y., Averkiev, S.V., Iomdina, E.N. et al. Changes in the physicochemical characteristics of rabbit sclera upon scleral reinforcement. BIOPHYSICS 52, 227–232 (2007). https://doi.org/10.1134/S0006350907020145

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  • DOI: https://doi.org/10.1134/S0006350907020145

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