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Analysis of the nucleotide sequence and electrostatic potential distribution in the Escherichia coli genome

  • Molecular Biophysics
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Abstract

Analysis of the oligonucleotide composition of the complete E. coli genome and its σ70-specific promoters shows that promoter DNA mainly contains AT-rich hexanucleotides that have functionally important physical properties (propensity to form ‘low-melting’ regions and helix bends). Comparative analysis of the electrostatic characteristics reveals that hexanucleotides corresponding to more electronegative surroundings are mostly found in promoter DNA.

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Abbreviations

SAXS:

small-angle x-ray scattering

SANS:

small-angle neutron scattering

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Authors and Affiliations

  1. Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia

    A. A. Sorokin, A. A. Osipov, P. M. Beskaravainyi & S. G. Kamzolova

Authors
  1. A. A. Sorokin
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  2. A. A. Osipov
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  3. P. M. Beskaravainyi
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  4. S. G. Kamzolova
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Additional information

Original Russian Text © A.A. Sorokin, A.A. Osipov, P.M. Beskaravianiyi, S.G. Kamzolova, 2007, published in Biofizika, 2007, Vol. 52, No. 2, pp. 223–227.

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Sorokin, A.A., Osipov, A.A., Beskaravainyi, P.M. et al. Analysis of the nucleotide sequence and electrostatic potential distribution in the Escherichia coli genome. BIOPHYSICS 52, 168–171 (2007). https://doi.org/10.1134/S0006350907020042

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  • DOI: https://doi.org/10.1134/S0006350907020042

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