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Cell adhesion proteins and α-fetoprotein. Similar structural motifs as prerequisites for common functions

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Abstract

This review summarizes and analyzes data on structural and functional relationships between cell adhesion proteins and α-fetoprotein (AFP), which play an important role in embryo-and carcinogenesis and act in synergism with growth factors. These two groups of proteins are mosaic, multimodular, and polyfunctional, and each of their modules can function independently through binding with its specific membrane receptor. Most cell adhesion proteins contain modules similar to epidermal growth factor (EGF) and also their repeats, which determine the involvement of these proteins in regulation of cell proliferation, differentiation, and apoptosis. These EGF-like modules are found to include short motifs similar to the fragment LDSYQCT of human AFP. Both direct and inverted AFP-like motifs are linked through a consensus octapeptide motif CXXGY/FXGX. Such AFP-like motifs of cell adhesion proteins and the tripeptide RGD found in AFP may be structural prerequisties for common functions of these groups of nonhomologous and unrelated proteins.

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Abbreviations

AFP:

α-fetoprotein

aa:

amino acid

BM:

basement membrane

ECM:

extracellular matrix

EGF:

epidermal growth factor

FAK:

focal adhesion kinase

ILK:

integrinlinked kinase

IGF:

insulin-like growth factor

MAPK:

mitogen-activated protein kinase

PDGF:

platelet-derived growth factor

PI-3K:

phosphatidylinositol-3-kinase

PKB:

protein kinase B

RGD:

arginyl-glycyl-aspartic acid

RTK:

receptor tyrosine kinase

TGF-α:

transforming growth factor-α

TNF-α:

tumor necrosis factor-α

VEGF:

vascular endothelial growth factor

References

  1. Takeichi, M. (1977) J. Cell Biol., 75, 464–474.

    Article  PubMed  CAS  Google Scholar 

  2. Ruoslahti, E., and Reed, J. C. (1994) Cell, 77, 477–478.

    Article  PubMed  CAS  Google Scholar 

  3. Gumbiner, B. M. (1996) Cell, 84, 345–357.

    Article  PubMed  CAS  Google Scholar 

  4. Ruoslahti, E., and Pierschbacher, M. D. (1987) Science, 238, 491–497.

    Article  PubMed  CAS  Google Scholar 

  5. Ruoslahti, E. (2003) Matrix Biol., 22, 459–465.

    Article  PubMed  CAS  Google Scholar 

  6. Engel, J. (1989) FEBS Lett., 251, 1–7.

    Article  PubMed  CAS  Google Scholar 

  7. Tatarinov, Yu. S. (1965) Vopr. Khim., 11, 20–24.

    CAS  Google Scholar 

  8. Abelev, G. I. (1971) Adv. Cancer Res., 14, 295–358.

    Article  PubMed  CAS  Google Scholar 

  9. Mizejewski, G. J. (1995) Crit. Rev. Eucaryot. Gene Expr., 5, 281–316.

    CAS  Google Scholar 

  10. Terentiev, A. A., and Moldogazieva, N. T. (2006) Biochemistry (Moscow), 71, 120–132.

    Article  CAS  Google Scholar 

  11. Terentiev, A. A. (1997) Vestn. Ros. Gos. Med. Univer., 1, 76–79.

    Google Scholar 

  12. Terentiev, A. A., and Tatarinov, Yu. S. (1999) Tumor Biol., 20,Suppl. 2, 44.

    Google Scholar 

  13. Kazimirsky, A. N., Salmasi, Zh. M., Makarkov, A. I., Terentiev, A. A., and Tatarinov, Yu. S. (1996) Ros. Zh. Gastroenterol. Gepatol. Proktol., 2, 62–66.

    Google Scholar 

  14. Kazimirsky, A. N., Salmasi, Zh. M., Semenova, L. Yu., Nadzhiorum Ngam-Asra, Bespalova, Zh. D., Kydryavtseva, E. V., Poryadin, G. V., and Terentiev, A. A. (2003) Vestn. Ros. Gos. Med. Univer., 3, 48–56.

    Google Scholar 

  15. Terentiev, A. A., Simonova, A. V., Arshinova, S. S., Kulakov, V. V., Bakhus, G. O., Pavlichenkov, A. V., Kudryavtseva, E. V., Bespalova, Zh. D., Ovchinnikov, M. V., Moldogazieva, N. T., and Tagirova, A. K. (2004) Immunologiya, 5, 279–281.

    Google Scholar 

  16. Moldogazieva, N. T., and Terentiev, A. A. (2006) Adv. Biol. Chem., 46, 99–148.

    CAS  Google Scholar 

  17. Mizejewski, G. J. (2001) Exp. Biol. Med., 226, 377–408.

    CAS  Google Scholar 

  18. Fisher, G., and Schachner, M. (1988) Brain Res., 471, 39–46.

    Google Scholar 

  19. Pierschbacher, M. D., and Ruoslahti, E. (1984) Nature, 309, 30–33.

    Article  PubMed  CAS  Google Scholar 

  20. Dedhar, S., Ruoslahti, E., and Pierschbacher, M. D. (1987) J. Cell Biol., 104, 585–593.

    Article  PubMed  CAS  Google Scholar 

  21. Plow, E. F., Pierschbacher, M. D., Ruoslahti, E., Marquerie, G., and Ginsberg, M. H. (1987) Blood, 70, 110–115.

    PubMed  CAS  Google Scholar 

  22. Hynes, R. O. (1992) Cell, 69, 11–25.

    Article  PubMed  CAS  Google Scholar 

  23. Doolittle, R. F. (1992) Science, 1, 192–200.

    Google Scholar 

  24. Hohenester, E., and Engel, J. (2002) Matrix Biol., 21, 115–128.

    Article  PubMed  CAS  Google Scholar 

  25. Khoshnoodi, J., Cartailler, J.-P., Alvares, K., Veis, A., and Hudson, B. J. (2006) J. Biol. Chem., 281, 38117–38121.

    Article  PubMed  CAS  Google Scholar 

  26. Ricard-Blum, S., and Ruggiero, F. (2005) Pathol. Biol. (Paris), 53, 430–442.

    CAS  Google Scholar 

  27. Brodsky, B., and Persikov, A. V. (2005) Adv. Protein Chem., 70, 301–339.

    Article  PubMed  CAS  Google Scholar 

  28. Veit, G., Kobbe, B., Keene, D. R., Paulsson, M., Koch, M., and Wagener, R. (2006) J. Biol. Chem., 281, 3494–3504.

    Article  PubMed  CAS  Google Scholar 

  29. Canty, E. G., and Kadler, K. E. (2005) J. Cell Sci., 118, 1341–1353.

    Article  PubMed  CAS  Google Scholar 

  30. Boot-Handford, R. P., Tuckwell, D. S., Plumb, D. A., Rock, C. F., and Poulsom, R. (2003) J. Biol. Chem., 278, 31067–31077.

    Article  PubMed  CAS  Google Scholar 

  31. Pace, J. M., Corrado, M., Missero, C., and Byers, P. H. (2003) Matrix Biol., 22, 3–14.

    Article  PubMed  CAS  Google Scholar 

  32. Koch, M., Laub, F., Zhou, P., Hahn, R. A., Tanaka, S., Burgeson, R. E., Gerecke, D. R., Ramirez, F., and Gordon, M. K. (2003) J. Biol. Chem., 278, 43236–43244.

    Article  PubMed  CAS  Google Scholar 

  33. Lamande, S. R., Morgelin, M., Adams, N. E., Selan, C., and Allen, J. M. (2006) J. Biol. Chem., 281, 16607–16614.

    Article  PubMed  CAS  Google Scholar 

  34. Ball, S. G., Baldock, C., Kielty, C. M., and Shuttleworth, C. A. (2001) J. Biol. Chem., 276, 7422–7430.

    Article  PubMed  CAS  Google Scholar 

  35. Christiano, A. M., Greenspan, D. S., Lee, S., and Uitto, J. (1994) J. Biol. Chem., 269, 20256–20262.

    PubMed  CAS  Google Scholar 

  36. Chen, M., Costa, F. K., Lindvay, C. R., Han, Y. P., and Woodley, D. T. (2002) J. Biol. Chem., 277, 2118–2124.

    Article  PubMed  CAS  Google Scholar 

  37. Franzke, C. W., Bruckner, P., and Bruckner-Tuderman, L. (2005) J. Biol. Chem., 280, 4005–4008.

    Article  PubMed  CAS  Google Scholar 

  38. Latvanlehto, A., Snellman, A., Tu, H., and Pihlajaniemi, T. (2003) J. Biol. Chem., 278, 37590–37599.

    Article  PubMed  CAS  Google Scholar 

  39. Areida, S. K., Reinhardt, D. P., Muller, P. K., Fietzek, P. P., Kowitz, J., Marinkovich, M. P., and Notbohm, H. (2001) J. Biol. Chem., 276, 1594–1601.

    Article  PubMed  CAS  Google Scholar 

  40. Kuznetsova, N. V., McBride, D. J., and Leikin, S. (2003) J. Mol. Biol., 331, 191–200.

    Article  PubMed  CAS  Google Scholar 

  41. Leikina, E., Mertts, M. V., Kuznetsova, N., and Leikin, S. (2002) Proc. Natl. Acad. Sci. USA, 99, 1314–1318.

    Article  PubMed  Google Scholar 

  42. Bulleid, N. J., Dalley, J. A., and Lees, J. F. (1997) EMBO J., 16, 6694–6701.

    Article  PubMed  CAS  Google Scholar 

  43. Lim, A. L., Doyle, S. A., Balian, G., and Smith, B. D. (1998) J. Cell. Biochem., 71, 216–232.

    Article  PubMed  CAS  Google Scholar 

  44. Doyle, S. A., and Smith, B. D. (1998) J. Cell. Biochem., 71, 233–242.

    Article  PubMed  CAS  Google Scholar 

  45. Hudson, B. G., Tryggvason, K., Sundaramoorthy, M., and Neilson, E. G. (2003) New Engl. J. Med., 348, 2543–2556.

    Article  PubMed  CAS  Google Scholar 

  46. Boutaud, A., Borza, D. B., Bondar, O., Gunwar, S., Netzer, K. O., Singh, N., Ninomiya, Y., Sado, Y., Noelken, M. E., and Hudson, B. G. (2000) J. Biol. Chem., 275, 30716–30724.

    Article  PubMed  CAS  Google Scholar 

  47. Li, D., Clark, C. C., and Myers, J. C. (2000) J. Biol. Chem., 275, 22339–22347.

    Article  PubMed  CAS  Google Scholar 

  48. Halfter, W., Dong, S., Schurer, B., and Cole, G. J. (1998) J. Biol. Chem., 273, 25404–25412.

    Article  PubMed  CAS  Google Scholar 

  49. Timpl, R. (1989) Eur. J. Biochem., 180, 487–502.

    Article  PubMed  CAS  Google Scholar 

  50. Timpl, R., and Brown, J. C. (1996) Bioessays, 18, 123–132.

    Article  PubMed  CAS  Google Scholar 

  51. Colorado, P. C., Torre, A., Kamphaus, G., Maeshima, Y., Hopfer, H., Takahashi, K., Volk, R., Zamborsky, E. D., Herman, S., and Sarkar, P. K. (2000) Cancer Res., 60, 2520–2526.

    PubMed  CAS  Google Scholar 

  52. Ramachandran, R., Dhanabal, M., Volk, R., Waterman, M. J. F., Segal, M., Lu, H., Knebelmann, B., and Sukhatme, V. P. (1999) Biochem. Biophys. Res. Commun., 255, 735–739.

    Article  Google Scholar 

  53. Sasaki, T., Larsson, H., Tisi, D., Claesson-Welsh, L., Hohenester, E., and Timpl, R. (2000) J. Mol. Biol., 301, 1179–1190.

    Article  PubMed  CAS  Google Scholar 

  54. Karihaloo, A., Karumanchi, S. A., Barasch, J., Jha, V., Nickel, C. H., Yang, J., Grisaru, S., Bush, K. T., Nigam, S., and Rosenblum, N. D. (2001) Proc. Natl. Acad. Sci. USA, 98, 12509–12514.

    Article  PubMed  CAS  Google Scholar 

  55. Hanai, J., Danabal, M., Karumanchi, S. A., Albanese, C., Waterman, M. J. F., Chan, B., Ramchandran, R., Pestell, R., and Sukhatme, V. P. (2002) J. Biol. Chem., 277, 16464–16469.

    Article  PubMed  CAS  Google Scholar 

  56. Carvalhaes, L. S., Gervasio, O. L., Guatimosim, C., Heljasvaara, R., Sormunen, R., Pihlajaniemi, T., and Kitten, G. T. (2006) Dev. Dyn., 235, 132–142.

    Article  PubMed  CAS  Google Scholar 

  57. Pedchenko, V., Zent, R., and Hudson, B. G. (2004) J. Biol. Chem., 279, 2772–2280.

    Article  PubMed  CAS  Google Scholar 

  58. Setty, S., Kim, Y., Fields, G. B., Clegg, D. O., Wayner, E. A., and Tsilibary, E. C. (1998) J. Biol. Chem., 273, 12244–12249.

    Article  PubMed  CAS  Google Scholar 

  59. Borza, C. M., Pozzi, A., Borza, D. B., Pedchenko, V., Hellmark, T., Hudson, B. G., and Zent, R. (2006) J. Biol. Chem., 281, 20932–20939.

    Article  PubMed  CAS  Google Scholar 

  60. Vogel, W. (1999) FASEB J., 13, S77–S82.

    PubMed  CAS  Google Scholar 

  61. Timpl, R., Rohde, H., Gehron-Robey, P., Rennard, S. I., Foidart, J. M., and Martin, G. (1979) J. Biol. Chem., 254, 9933–9937.

    PubMed  CAS  Google Scholar 

  62. Chung, A. E., Jaffe, R., Freeman, I. L., Vergnes, J. P., Braginski, J. E., and Carlin, B. (1979) Cell, 16, 277–287.

    Article  PubMed  CAS  Google Scholar 

  63. Tunggal, P., Smyth, N., Paulsson, M., and Ott, M. C. (2000) Microsc. Res. Tech., 51, 214–227.

    Article  PubMed  CAS  Google Scholar 

  64. Colognato, H., Winkelmann, D. A., and Yurchenco, P. D. (1999) J. Cell. Biol., 145, 619–631.

    Article  PubMed  CAS  Google Scholar 

  65. Sasaki, T., Fassler, R., and Hohenester, E. (2004) J. Cell. Biol., 164, 959–963.

    Article  PubMed  CAS  Google Scholar 

  66. Yurchenco, P., and Cheng, Y. S. (1993) J. Biol. Chem., 268, 17286–17299.

    PubMed  CAS  Google Scholar 

  67. Beck, K., Hunter, I., and Engel, J. (1990) FASEB J., 4, 148–160.

    PubMed  CAS  Google Scholar 

  68. Timpl, R., Tisi, D., Talts, J. F., Andac, Z., Sasaki, T., and Hohenester, E. (2000) Matrix Biol., 19, 309–317.

    Article  PubMed  CAS  Google Scholar 

  69. Sasaki, T., and Timpl, R. (2001) FEBS Lett., 509, 181–185.

    Article  PubMed  CAS  Google Scholar 

  70. Colognato, H., and Yurchenco, P. D. (2000) Dev. Dyn., 218, 213–234.

    Article  PubMed  CAS  Google Scholar 

  71. Li, S., Edgar, D., Fassler, R., Wadsworth, W., and Yurchenco, P. D. (2003) Dev. Cell, 4, 613–624.

    Article  PubMed  CAS  Google Scholar 

  72. Miner, J. H., Cunningham, J., and Sanes, J. R. (1998) J. Cell Biol., 143, 1713–1723.

    Article  PubMed  CAS  Google Scholar 

  73. Costell, M., Gustafsson, E., Aszodi, A., Morgelin, M., Bloch, W., Hunziker, E., Addicks, K., Timpl, R., and Fassler, T. (1999) J. Cell Biol., 147, 1109–1122.

    Article  PubMed  CAS  Google Scholar 

  74. Poschl, E., Schlotzer-Schrehardt, U., Brachvogel, B., Saito, K., Ninomiya, Y., and Mayer, U. (2004) Development, 131, 1619–1628.

    Article  PubMed  CAS  Google Scholar 

  75. Hallmann, R., Horn, N., Selg, M., Wendler, O., Pausch, F., and Sorokin, L. M. (2005) Physiol. Rev., 85, 979–1000.

    Article  PubMed  CAS  Google Scholar 

  76. Fujiwara, H., Kikkawa, Y., Sanzen, N., and Sekiguchi, K. (2001) J. Biol. Chem., 276, 1755–1758.

    Google Scholar 

  77. Yamada, K. M. (1989) Curr. Opin. Cell. Biol., 1, 956–963.

    Article  PubMed  CAS  Google Scholar 

  78. Hocking, D. C., Sottile, J., and McKeown-Longo, P. J. (1998) J. Cell Biol., 141, 241–253.

    Article  PubMed  CAS  Google Scholar 

  79. Ruoslahti, E. (1984) Cancer Metastasis Rev., 3, 43–51.

    Article  PubMed  CAS  Google Scholar 

  80. Stubbs, J. D., Lekutis, C., Singer, K. L., Bui, A., Yuzuki, D., Srinivasan, U., and Parry, G. (1990) Proc. Natl. Acad. Sci. USA, 87, 8417–8421.

    Article  PubMed  CAS  Google Scholar 

  81. Peterson, J. A., Couto, J. R., Taylor, M. R., and Ceriani, R. L. (1995) Cancer Res., 55,Suppl. 23, S5847–S5851.

    Google Scholar 

  82. Giuffrida, M. G., Cavaletto, M., Giunta, C., Conti, A., and Godovac-Zimmermann, J. (1998) J. Protein Chem., 17, 143–148.

    Article  PubMed  CAS  Google Scholar 

  83. Couto, J. R., Taylor, M. R., Godwin, S. G., Ceriani, R. L., and Peterson, J. A. (1996) DNA Cell Biol., 15, 281–286.

    Article  PubMed  CAS  Google Scholar 

  84. Taylor, M. R., Couto, J. R., Scallan, C. D., Ceriani, R. L., and Peterson, J. A. (1997) DNA Cell Biol., 16, 861–869.

    Article  PubMed  CAS  Google Scholar 

  85. Andersen, M. H., Graversen, H., Fedosov, S. N., Petersen, T. E., and Rasmussen, J. T. (2000) Biochemistry, 39, 6200–6206.

    Article  PubMed  CAS  Google Scholar 

  86. Shi, J., and Gilbert, G. E. (2003) Blood, 101, 2628–2636.

    Article  PubMed  CAS  Google Scholar 

  87. Shi, J., Heegaard, C. W., Rasmussen, J. T., and Gilbert, G. E. (2004) Biochim. Biophys. Acta, 1667, 82–90.

    Article  PubMed  CAS  Google Scholar 

  88. Haeqqvist, B., Naeslund, J., Sletten, K., Westermark, G. T., Mucchiano, G., Tjernberg, L. O., Nordstend, C., Engstrom, U., and Westermark, P. (1999) Proc. Natl. Acad. Sci. USA, 96, 8669–8674.

    Article  Google Scholar 

  89. Reches, M., and Gazit, E. (2004) Amyloid, 11, 81–89.

    Article  PubMed  CAS  Google Scholar 

  90. Larsson, A., Peng, S., Persson, H., Rosenbloom, J., Abrams, W. R., Wassberg, E., Thelin, S., Sletten, K., Gerwins, P., and Westermark, P. (2006) Amyloid, 13, 78–85.

    Article  PubMed  CAS  Google Scholar 

  91. Deak, F., Wagener, R., Kiss, I., and Paulsson, M. (1999) Matrix Biol., 18, 55–66.

    Article  PubMed  CAS  Google Scholar 

  92. Wu, J. J., and Eyre, D. R. (1998) J. Biol. Chem., 273, 17433–17438.

    Article  PubMed  CAS  Google Scholar 

  93. Klatt, A. R., Nitsche, P. D., Kobbe, B., Morgelin, M., Paulsson, M., and Wagener, R. (2000) J. Biol. Chem., 275, 3999–4006.

    Article  PubMed  CAS  Google Scholar 

  94. Frank, S., Shulthess, T., Landwehr, R., Lustiq, A., Mini, T., Jeno, P., Enqel, J., and Kammerer, R. A. (2002) J. Biol. Chem., 277, 1907–19079.

    Article  CAS  Google Scholar 

  95. Piecha, D., Muratoglu, S., Morgelin, M., Hauser, N., Studer, D., Kiss, I., Paulsson, M., and Deak, F. (1999) J. Biol. Chem., 274, 13353–13362.

    Article  PubMed  CAS  Google Scholar 

  96. Piecha, D., Wiberg, C., Morqelin, M., Reinhardt, D. P., Deak, F., Maurer, P., and Paulsson, M. (2002) Biochem. J., 367, 715–721.

    Article  PubMed  CAS  Google Scholar 

  97. Korpos, E., Molnar, A., Papp, P., Kiss, I., Orosz, L., and Deak, F. (2005) Matrix Biol., 24, 124–135.

    Article  PubMed  CAS  Google Scholar 

  98. Mates, L., Nicalae, C., Morqelin, M., Deak, F., Kiss, I., and Aszodi, A. (2004) Matrix Biol., 23, 195–204.

    Article  PubMed  CAS  Google Scholar 

  99. Deak, F., Piecha, D., Bachrati, C., Paulsson, M., and Kiss, I. (1997) J. Biol. Chem., 272, 9268–9274.

    Article  PubMed  CAS  Google Scholar 

  100. Zhang, Y. and Chen, Q. (2000) J. Biol. Chem., 275, 32628–32634.

    Article  PubMed  CAS  Google Scholar 

  101. Takeichi, M. (1988) Development, 102, 639–655.

    PubMed  CAS  Google Scholar 

  102. Takeichi, M. (1991) Science, 251, 1451–1455.

    Article  PubMed  CAS  Google Scholar 

  103. Shirayoshi, Y., Hatta, K., Hosoda, M., Tsunasawa, S., Sakiyama, F., and Takeichi, M. (1986) EMBO J., 5, 2485–2488.

    PubMed  CAS  Google Scholar 

  104. Shapiro, L., Fannon, A. M., Kwong, P. D., Thompson, A., Lehman, M. S., Grubel, G., Leqrand, J. F., Als-Nielsen, J., Colman, D. R., and Hendrickson, W. A. (1995) Nature, 374, 327–337.

    Article  PubMed  CAS  Google Scholar 

  105. Gooding, J. M., Yap, K. L., and Ikura, M. (2004) BioEssays, 26, 497–511.

    Article  PubMed  CAS  Google Scholar 

  106. Takahashi, K., Suzuki, K., and Tsukatani, Y. (1997) Oncogene, 15, 71–78.

    Article  PubMed  CAS  Google Scholar 

  107. Zhuang, S., Yan, Y., Han, J., and Schnellmann, R. G. (2005) J. Biol. Chem., 280, 21036–21042.

    Article  PubMed  CAS  Google Scholar 

  108. Gumbiner, B. M. (1992) Cell, 69, 385–387.

    Article  PubMed  CAS  Google Scholar 

  109. Takeichi, M. (1993) Curr. Opin. Cell. Biol., 5, 806–811.

    Article  PubMed  CAS  Google Scholar 

  110. Van Marck, V. V., Stove, C., van den Bossche, K., Stove, V., Paredes, J., van der Haeghen, Y., and Bracke, M. (2005) Cancer Res., 65, 8774–8783.

    Article  PubMed  CAS  Google Scholar 

  111. Liang, O. D., Korff, T., Eckhard, J., Rifaat, J., Baal, N., Herr, F., Preissner, K. T., and Zygmunt, M. (2004) J. Clin. Endocrin. Metabol., 80, 1415–1422.

    Article  CAS  Google Scholar 

  112. Li, M. S., Li, P. F., Yang, F. Y., He, S. P., Du, G. G., and Li, G. (2002) Cell Res., 12, 151–156.

    Article  PubMed  Google Scholar 

  113. Li, M. S., Li, P. F., Chen, Q., Du, G. G., and Li, G. (2004) World J. Gastroenterol., 10, 819–824.

    PubMed  CAS  Google Scholar 

  114. Kleiger, G., Grothe, R., Mallick, P., and Eisenberg, D. (2002) Biochemistry, 41, 5990–5997.

    Article  PubMed  CAS  Google Scholar 

  115. Giancotti, F. G., and Tarone, G. (2003) Annu. Rev. Cell. Dev. Biol., 19, 173–206.

    Article  PubMed  CAS  Google Scholar 

  116. Moro, L., Venturino, M., Bozzo, C., Silengo, L., Altruda, F., Beguinot, L., Tarone, G., and Defilippi, P. (1998) EMBO J., 17, 6622–6632.

    Article  PubMed  CAS  Google Scholar 

  117. Soldi, R., Mitola, S., Strasly, M., Defilippi, P., Tarone, G., and Bussolino, F. (1999) EMBO J., 18, 882–892.

    Article  PubMed  CAS  Google Scholar 

  118. Akiyama, S. K. (1996) Hum. Cell, 9, 181–186.

    PubMed  CAS  Google Scholar 

  119. Giancotti, F. G., and Ruoslahti, E. (1999) Science, 285, 1028–1032.

    Article  PubMed  CAS  Google Scholar 

  120. Berman, A. E., Kozlova, N. I., and Morozevich, G. E. (2003) Biochemistry (Moscow), 12, 1284–1299.

    Article  Google Scholar 

  121. Hehlgans, S., Haase, M., and Cordes, N. (2007) Biochim. Biophys. Acta, 1775, 63–80.

    Google Scholar 

  122. Takagi, J., Petre, B. M., Walz, T., and Springer, T. A. (2002) Cell, 110, 599–611.

    Article  PubMed  CAS  Google Scholar 

  123. Hirsch, E., Barbaris, L., Brancaccio, M., Azzolino, O., Xu, D., Kyriakis, J. M., Silengo, L., Giancotti, F. G., Tarone, G., Fassler, R., and Altruda, F. (2002) J. Cell Biol., 157, 481–492.

    Article  PubMed  CAS  Google Scholar 

  124. Xiong, J. P., Stehle, T., Zhang, R., Joachimiak, A., Frech, M., Goodman, S. L., and Arnaout, M. A. (2002) Science, 296, 151–155.

    Article  PubMed  CAS  Google Scholar 

  125. Xiao, T., Takagi, J., Coller, B. S., Wang, J. H., and Springer, T. A. (2004) Nature 432, 59–67.

    Article  PubMed  CAS  Google Scholar 

  126. Bella, J., and Humphries, M. J. (2005) BMC Struct. Biol., 5.

  127. Cary, L. A., and Guan, J. L. (1999) Front. Biosci., 4, D102–D113.

    Article  PubMed  CAS  Google Scholar 

  128. Wu, C., and Dedhar, S. (2001) J. Cell Biol., 155, 505–510.

    Article  PubMed  CAS  Google Scholar 

  129. Mainiero, F., Murgia, C., Wary, K. K., Curatola, A. M., Pepe, A., Blumenberg, M., Westwick, J. K., Der, C. J., and Giancotti, F. G. (1997) EMBO J., 16, 2365–2375.

    Article  PubMed  CAS  Google Scholar 

  130. Wary, K. K., Mainiero, F., Isakoff, S. J., Marcantonio, E. E., and Giancotti, F. G. (1996) Cell, 87, 733–743.

    Article  PubMed  CAS  Google Scholar 

  131. Gilmore, A. P., and Romer, L. H. (1996) Mol. Biol. Cell, 7, 1209–1224.

    PubMed  CAS  Google Scholar 

  132. Wennerberg, K., Armulik, A., Sakai, T., Karlsson, M., Fassler, R., Schaefer, E. M., Mosher, D. F., and Johansson, S. (2000) Mol. Cell. Biol., 20, 5758–5765.

    Article  PubMed  CAS  Google Scholar 

  133. Reiske, H. R., Kao, S. C., Cary, L. A., Guan, J. L., Lai, J. F., and Chen, H. C. (1999) J. Biol. Chem., 274, 12361–12366.

    Article  PubMed  CAS  Google Scholar 

  134. Richardson, A., Malik, R. K., Hildebrand, J. D., and Parsons, J. T. (1997) Mol. Cell. Biol., 17, 6906–6914.

    PubMed  CAS  Google Scholar 

  135. Klemke, R. L., Leng, J., Molander, R., Brooks, P. C., Vuori, K., and Cheresh, D. A. (1998) J. Cell Biol., 140, 961–972.

    Article  PubMed  CAS  Google Scholar 

  136. Schaepfer, D. D., Jones, K. C., and Hunter, T. (1998) Mol. Cell Biol., 18, 2571–2585.

    Google Scholar 

  137. Barberis, L., Wary, K. K., Fjucci, G., Liu, F., Hirsch, E., Brancaccio, M., Altruda, F., Tarone, G., and Giancotti, F. C. (2000) J. Biol. Chem., 275, 36532–36540.

    Article  PubMed  CAS  Google Scholar 

  138. Oktay, M., Wary, K. K., Dans, M., Birge, R. B., and Giancotti, F. G. (1999) J. Biol. Chem., 145, 1461–1497.

    CAS  Google Scholar 

  139. Karin, M., Liu, Z.-G., and Zandi, E. (1997) Curr. Opin. Cell Biol., 9, 240–246.

    Article  PubMed  CAS  Google Scholar 

  140. Reif, S., Lang, A., Lindquist, J. N., Yata, Y., Gabele, E., Scanga, A., Brenner, D. A., and Rippe, R. A. (2003) J. Biol. Chem., 278, 8083–8090.

    Article  PubMed  CAS  Google Scholar 

  141. Hannigan, G. E., Leung-Hagesteijn, C., Fitz-Gibbon, L., Coppolino, M. G., Radeva, G., Filmus, J., Bell, J. C., and Dedhar, S. (1996) Nature, 379, 91–96.

    Article  PubMed  CAS  Google Scholar 

  142. Grashoff, C., Thievessen, I., Lorenz, K., and Ussar, S. (2004) Curr. Opin. Cell. Biol., 16, 565–571.

    Article  PubMed  CAS  Google Scholar 

  143. Tu, Y., Li, F., Goicoechea, S., and Wu, C. (1999) Mol. Cell. Biol., 19, 2425–2434.

    PubMed  CAS  Google Scholar 

  144. Tu, Y., Huang, Y., Zhang, Z., Hua, Y., and Wu, C. (2001) J. Cell Biol., 153, 585–598.

    Article  PubMed  CAS  Google Scholar 

  145. Wu, C. (2004) Biochim. Biophys. Acta, 1692, 55–62.

    PubMed  CAS  Google Scholar 

  146. Tu, Y., Li, F., and Wu, C. (1998) Mol. Biol. Cell, 9, 3367–3382.

    PubMed  CAS  Google Scholar 

  147. Dedhar, S. (2000) Curr. Opin. Cell Biol., 12, 250–256.

    Article  PubMed  CAS  Google Scholar 

  148. Persad, S., and Dedhar, S. (2003) Cancer Metastasis Rev., 22, 375–384.

    Article  PubMed  CAS  Google Scholar 

  149. Liu, E., Sinha, S., Williams, C., Cyrille, M., Heller, E., Snapper, S. B., Geogropoulos, K., St-Arnaud, R., Force, T., Dedhar, S., and Gerszten, R. E. (2005) Mol. Cell. Biol., 25, 11145–11155.

    Article  PubMed  CAS  Google Scholar 

  150. Gretski, V., Mars, W. M., Bowen, W. C., Barua, L., Yang, Y., Guo, L., St-Arnaud, R., Dedhar, S., and Michalopoulos, G. K. (2007) Hepatology, 45, 1025–1034.

    Article  CAS  Google Scholar 

  151. Giancotti, F. G. (1997) Curr. Opin. Cell Biol., 9, 691–700.

    Article  PubMed  CAS  Google Scholar 

  152. Howe, A., Aplin, A. E., Alahari, S. K., and Juliano, R. L. (1998) Curr. Opin. Cell Biol., 10, 220–231.

    Article  PubMed  CAS  Google Scholar 

  153. Ilic, D., Furuta, Y., Kanazawa, S., Takeda, N., Sobue, K., Nakatsuji, N., Nomura, S., Fujimoto, J., Okada, M., and Yamamoto, T. (1995) Nature, 377, 539–544.

    Article  PubMed  CAS  Google Scholar 

  154. Ilic, D., Almeida, E. A., Schlaepfer, D. D., Dazin, P., Aizawa, S., and Damsky, C. H. (1998) J. Cell Biol., 143, 547–560.

    Article  PubMed  CAS  Google Scholar 

  155. Giancotti, F. G., and Tarone, G. (2003) Annu. Rev. Cell Dev. Biol., 19, 173–206.

    Article  PubMed  CAS  Google Scholar 

  156. Short, S. M., Talbott, G. A., and Juliano, R. L. (1998) Mol. Biol. Cell., 8, 1969–1980.

    Google Scholar 

  157. Hutchings, H., Ortega, N., and Plouet, J. (2003) FASEB J., 17, 1520–1522.

    PubMed  CAS  Google Scholar 

  158. Masson-Gadais, B., Houle, F., Laferriere, J., and Huot, J. (2003) Cell. Stress Chaperones, 8, 37–52.

    Article  PubMed  CAS  Google Scholar 

  159. Davis, G. E., and Senger, D. R. (2005) Circulation Res., 97, 1093–1107.

    Article  PubMed  CAS  Google Scholar 

  160. Silvestre, J. S., Thery, C., Hamard, G., Boddaert, J., Aguilar, B., Delcayre, A., Houbron, C., Tamarat, R., Blanc-Brude, O., Heeneman, S., Clergue, M., Duriez, M., Merval, R., Levy, B., Tedgui, A., Amigorena, S., and Mallat, Z. (2005) Nat. Med., 11, 499–506.

    Article  PubMed  CAS  Google Scholar 

  161. Carloni, V., Pinzani, M., Giusti, S., Romanelli, R. G., Parola, M., Bellomo, G., Failli, P., Hamilton, A. D., Sebti, S. M., Laffi, G., and Gentilini, P. (2000) Hepatology, 31, 131–140.

    Article  PubMed  CAS  Google Scholar 

  162. Carloni, V., Defranco, R. M., Caligiuri, A., Gentilini, A., Sciametta, S. C., Lottini, B., Gentilini, P., and Pinzani, M. (2002) Hepatology, 36, 582–591.

    Article  PubMed  CAS  Google Scholar 

  163. Tai, Y. Y., Podar, K., Catley, L., Tseng, Y. H., Akiyama, M., Shringarpure, R., Burger, T. R., Hideshima, T., Chauchasn, D., Mitsiades, N., Richardson, P., Munshi, N. C., Kahn, C. R., Mitsiades, C., and Anderson, K. C. (2003) Cancer Res., 63, 5850–5858.

    PubMed  CAS  Google Scholar 

  164. Assoian, R. K. (1997) J. Cell Biol., 136, 1–4.

    Article  PubMed  CAS  Google Scholar 

  165. Schwartz, M. A., and Richard, K. (2001) J. Cell Sci., 114, 2553–2560.

    PubMed  CAS  Google Scholar 

  166. Walker, J. L., and Assoian, R. K. (2005) Cancer Metastasis Rev., 24, 383–393.

    Article  PubMed  CAS  Google Scholar 

  167. Ruoslahti, E. (1996) Tumor Biol., 17, 117–124.

    Article  CAS  Google Scholar 

  168. Stromblad, S., and Cheresh, D. A. (1996) Chem. Biol., 3, 881–885.

    Article  PubMed  CAS  Google Scholar 

  169. Ilan, N., Mahooti, S., and Madri, J. A. (1998) J. Cell Sci., 111,Pt. 24, 3621–3631.

    PubMed  CAS  Google Scholar 

  170. Aoudjit, F., and Vuori, K. (2001) J. Cell. Biol., 152, 633–643.

    Article  PubMed  CAS  Google Scholar 

  171. Chavakis, E., and Dimmeler, S. (2002) Arterioscler. Thromb. Vasc. Biol., 22, 887–893.

    Article  PubMed  CAS  Google Scholar 

  172. Brooks, P. C., Montgomery, A. M., Rosenfeld, M., Reisfeld, R. A., Hu, T., Klier, G., and Cheresh, D. A. (1994) Cell, 79, 1157–1164.

    Article  PubMed  CAS  Google Scholar 

  173. Ruegg, C., Yilmaz, A., Bieler, G., Bamat, J., Chaubert, P., and Lejeune, F. J. (1998) Nat. Med., 4, 408–414.

    Article  PubMed  CAS  Google Scholar 

  174. Bader, B. L., Rayburn, H., Crowley, D., and Hynes, R. O. (1998) Cell, 95, 507–519.

    Article  PubMed  CAS  Google Scholar 

  175. Kozlova, N. I., Morozevich, G. E., Chubukina, A. N., and Berman, A. E. (2001) Oncogene, 20, 4710–4717.

    Article  PubMed  CAS  Google Scholar 

  176. Reynolds, L. E., Bader, B. L., Wyder, L., Lively, J. C., Taverna, D., Robinson, S. D., Huang, X., Sheppard, D., Hynes, R. O., and Hodivala-Dilke, K. M. (2002) Nat. Med., 8, 27–34.

    Article  PubMed  CAS  Google Scholar 

  177. Xia, H., Nho, R. S., Kahm, J., Kleidon, J., and Henke, C. (2004) J. Biol. Chem., 279, 33024–33034.

    Article  PubMed  CAS  Google Scholar 

  178. Nho, R. S., Xia, H., Kahm, J., Kleidon, J., Diebold, D., and Henke, C. A. (2005) J. Biol. Chem., 280, 2663–2669.

    Article  CAS  Google Scholar 

  179. Rinoul, R. C., and Sethi, T. (2002) Clin. Sci. (London), 102, 417–424.

    Google Scholar 

  180. Gendron, S., Couture, J., and Aoudjit, F. (2003) J. Biol. Chem., 278, 48633–48643.

    Article  PubMed  CAS  Google Scholar 

  181. Huang, D., Khoe, M., Befekadu, M., Chung, S., Takata, Y., Ilic, D., and Bryer-Ash, M. (2007) Am. J. Physiol. Cell Physiol., 292, C1339–C1352.

    Article  PubMed  CAS  Google Scholar 

  182. Elliot, T., and Sethi, T. (2002) Expert Rev. Anticancer Ther., 2, 449–459.

    Article  Google Scholar 

  183. Maubant, S., Staedel, C., and Gauduchon, P. (2002) Bull. Cancer, 89, 923–934.

    PubMed  Google Scholar 

  184. Meyer, N., Duensing, S., Anastyassiou, G., Brevis Nunez, F., Grosse, J., Ganser, A., and Atzpodien, J. (1999) Anticancer Res., 19, 1509–1512.

    PubMed  CAS  Google Scholar 

  185. Morozevich, G. E., Kozlova, N. I., Preobrazhenskaya, M. E., Ushakova, N. A., El’tsov, N. A., Shtil, A. A., and Berman, A. E. (2006) Biochemistry (Moscow), 71, 489–495.

    Article  CAS  Google Scholar 

  186. Kozlova, N. I., Morozevich, G. E., Shtil, A. A., and Berman, A. E. (2004) Biochem. Biophys. Res. Commun., 316, 1173–1177.

    Article  PubMed  CAS  Google Scholar 

  187. Pucci, P., Siliciano, R., Malorni, A., Marino, G., Tecce, M. F., Ceccarini, C., and Terrana, B. (1991) Biochemistry, 30, 5061–5066.

    Article  PubMed  CAS  Google Scholar 

  188. Morinaga, T., Sakai, M., Wegmann, T. G., and Namaoki, T. (1983) Proc. Natl. Acad. Sci. USA, 80, 4604–4608.

    Article  PubMed  CAS  Google Scholar 

  189. Dudich, I., Tokhtamysheva, N., Semenkova, L., Dudich, E., Hellman, Y., and Korpela, T. (1999) Biochemistry, 38, 10406–10414.

    Article  PubMed  CAS  Google Scholar 

  190. Luft, A. J., and Loscheider, F. L. (1983) Biochemistry, 22, 5971–5978.

    Article  Google Scholar 

  191. Zizkovsky, V., Strop, P., Korcakova, J., Havranova, M., and Mikes, F. (1983) Ann. N. Y. Acad. Sci., 417, 49–56.

    Article  PubMed  CAS  Google Scholar 

  192. Salmasi, J. M., Kazimirsky, A. N., Terentiev, A. A., Poryadin, G. V., Kudryavtseva, E. V., and Tatarinov, Yu. S. (1999) Tumor Biol., 20,Suppl. 2, 43.

    Google Scholar 

  193. Terentiev, A. A., Simonova, A. V., Arshinova, S. S., Kulakov, V. V., Bahus, G. O., Kudryavtseva, E. V., Bespalova, J. D., Ovchinnikov, M. V., and Tatarinov, Yu. S. (2003) Tumor Biol., 24,Suppl. 1, 54.

    Google Scholar 

  194. Moldogazieva, N. T., Terentiev, A. A., and Shaitan, K. V. (2005) Biomed. Khim., 51, 127–151.

    PubMed  CAS  Google Scholar 

  195. Kazimirsky, A. N., Terentiev, A. A., Salmasi, J. M., and Poryadin, G. V. (2001) Russ. J. Immunol., 6, 394–398.

    Google Scholar 

  196. Leffert, H. L., and Sell, S. (1974) J. Cell Biol., 61, 823–829.

    Article  PubMed  CAS  Google Scholar 

  197. Hamel, S., Hoskin, D. W., Hooper, D. C., and Murgita, R. A. (1987) in Biological Activities of Alpha-Fetoprotein (Mizejewski, G. J., and Jacobson, H. I., eds.) CRC Press, Florida, pp. 167–177.

    Google Scholar 

  198. Soto, A. M., and Sonnenschein, C. (1980) Proc. Natl. Acad. Sci. USA, 77, 2084–2087.

    Article  PubMed  CAS  Google Scholar 

  199. Mizejewski, G. J., Vonnegut, M., and Jacobson, H. I. (1983) Proc. Natl. Acad. Sci. USA, 80, 2733–2737.

    Article  PubMed  CAS  Google Scholar 

  200. Allen, S. H. G., Bennett, J. A., Mizejewski, G. J., Andersen, T. T., Ferraris, S., and Jacobson, H. I. (1993) Biochim. Biophys. Acta, 1202, 135–142.

    PubMed  CAS  Google Scholar 

  201. Dudich, E. A., Semenkova, L. V., Gorbatova, E. A., Dudich, A. V., Khromikh, L. M., Grechko, G. K., and Sukhikh, G. T. (1998) Tumor Biol., 19, 30–40.

    Article  CAS  Google Scholar 

  202. Toder, V., Bland, M., Gold-Gefte, L., and Nebel, J. (1983) Placenta, 4, 79–86.

    Article  PubMed  CAS  Google Scholar 

  203. Wang, X. W., and Xie, H. (1999) Life Sci., 64, 17–23.

    Article  PubMed  CAS  Google Scholar 

  204. Keel, B. A., Eddy, K. B., Cho, S., and May, J. V. (1991) Mol. Reprod. Dev., 30, 112–118.

    Article  PubMed  CAS  Google Scholar 

  205. Keel, B. A., Eddy, K. B., Cho, S., Gangrade, B. K., and May, J. V. (1992) Endocrinology, 130, 3715–3717.

    Article  PubMed  CAS  Google Scholar 

  206. Leal, J. A., Gangrade, B. K., Kiser, J. L., May, J. V., and Keel, B. A. (1991) Steroids, 56, 247–251.

    Article  PubMed  CAS  Google Scholar 

  207. Li, M. S., Li, P. F., Du, G. G., and Li, G. (2002) Clin. J. Biochem. Mol. Biol., 18, 750–754.

    CAS  Google Scholar 

  208. Laderoute, M. P., and Pilarski, L. M. (1994) Anticancer Res., 14, 2429–2438.

    PubMed  CAS  Google Scholar 

  209. Semenkova, L. N., Dudich, E. I., Dudich, I. V., Shingarova, L. N., and Korobko, V. G. (1997) Tumor Biol., 18, 30–40.

    Article  CAS  Google Scholar 

  210. Cavin, L. G., Venkatraman, M., Factor, V. M., Kaur, S., Schroeder, I., Mercurio, F., Beg, A. A., Thorgeirsson, S. S., and Arsura, M. (2004) Cancer Res., 64, 7030–7038.

    Article  PubMed  CAS  Google Scholar 

  211. Sah, J. F., Balasubramanian, S., Eckert, R. L., and Rorke, E. A. (2004) J. Biol. Chem., 279, 12755–12762.

    Article  PubMed  CAS  Google Scholar 

  212. Dudich, E., Semenkova, L., Dudich, I., Gorbatova, E., Tokhtamisheva, N., Tatulov, E., Nikolaeva, M., and Sukhikh, G. (1999) Eur. J. Biochem., 266, 750–761.

    Article  PubMed  CAS  Google Scholar 

  213. Semenkova, L., Dudich, E., Dudich, I., Tokhtamisheva, N., Tatulov, E., Okruzhnov, Yu., Garcia-Foncillas, J., Palop-Cubillo, J. A., and Korpela, T. (2003) Eur. J. Biochem., 270, 4388–4399.

    Article  PubMed  CAS  Google Scholar 

  214. Villacampa, M. J., Moro, R., Naval, J., Failly-Crepin, C., Lampreave, F., and Uriel, J. (1984) Biochem. Biophys. Res. Commun., 122, 1322–1327.

    Article  PubMed  CAS  Google Scholar 

  215. Torres, J. M., Laborda, J., Naval, J., Darracq, N., Calvo, M., Mishal, Z., and Uriel, J. (1989) Mol. Immunol., 26, 851–857.

    Article  PubMed  CAS  Google Scholar 

  216. Naval, J., Villacampa, M. J., Goguel, A. F., and Uriel, J. (1985) Proc. Natl. Acad. Sci. USA 82, 3301–3304.

    Article  PubMed  CAS  Google Scholar 

  217. Torres, J. M., Darracq, N., and Uriel, J. (1992) Biochim. Biophys. Acta, 1159, 60–66.

    PubMed  CAS  Google Scholar 

  218. Suzuki, Y., Zeng, C. Q. Y., and Alpert, E. (1992) J. Clin. Invest., 90, 1530–1536.

    Article  PubMed  CAS  Google Scholar 

  219. Uriel, J., Naval, J., and Laborda, J. (1987) J. Biol. Chem., 262, 3579–3585.

    PubMed  CAS  Google Scholar 

  220. Esteban, C., Geuskens, M., and Uriel, J. (1991) Int. J. Cancer, 49, 425–430.

    Article  PubMed  CAS  Google Scholar 

  221. Alava, M. A., Sturralde, M., Lampreave, F., and Pineiro, A. (1999) Tumor Biol., 20, 52–64.

    Article  CAS  Google Scholar 

  222. Moro, R., Tamaoki, T., Wegmann, T. J., Longnecker, B. M., and Laderoute, M. P. (1993) Tumor Biol., 14, 116–130.

    Article  CAS  Google Scholar 

  223. Ogiso, H., Ishitani, R., Nureki, O., Fukai, S., Yamanaka, M., Kim, J.-H., Saito, K., Sakamoto, A., Inoue, M., Shirouzu, M., and Yokoyama, S. (2002) Cell, 110, 775–787.

    Article  PubMed  CAS  Google Scholar 

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  1. Department of Biochemistry, Russian State Medical University, ul. Ostrovityanova 1, 117997, Moscow, Russia

    A. A. Terentiev & N. T. Moldogazieva

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Original Russian Text © A. A. Terentiev, N. T. Moldogazieva, 2007, published in Biokhimiya, 2007, Vol. 72, No. 9, pp. 1133–1152.

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Terentiev, A.A., Moldogazieva, N.T. Cell adhesion proteins and α-fetoprotein. Similar structural motifs as prerequisites for common functions. Biochemistry Moscow 72, 920–935 (2007). https://doi.org/10.1134/S0006297907090027

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