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Biochemistry of prostaglandins A

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Abstract

This review considers modern concepts on the structural-functional properties and antiproliferative, antitumor, and antiviral effects of cyclopentenone prostaglandins A and mechanisms underlying their actions. Possible directions of pharmacological application of these compounds and their analogs are discussed.

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Abbreviations

COX:

cyclooxygenase

PC:

prostacyclins

PG:

prostaglandins

Tx:

thromboxanes

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  1. Belarus State University, pr. Nezavisimosty 4, 220050, Minsk, Belarus

    A. I. Hubich & M. V. Sholukh

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  1. A. I. Hubich
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  2. M. V. Sholukh
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Correspondence to M. V. Sholukh.

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Original Russian Text © A. I. Hubich, M. V. Sholukh, 2006, published in Biokhimiya, 2006, Vol. 71, No. 3, pp. 293–304.

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Hubich, A.I., Sholukh, M.V. Biochemistry of prostaglandins A. Biochemistry (Moscow) 71, 229–238 (2006). https://doi.org/10.1134/S0006297906030011

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