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X-ray diffraction studies of 5-functionalized 1,2,3,4-tetrahydropyrimidin-2-ones(thiones): II. Molecular and crystal structures of 5-benzoyl-4,6-dimethyl-1,2,3,4-tetrahydropyrimidine-2-thione and ethyl 6-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

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Abstract

The structures of two new tetrahydropyrimidine-2-thiones, namely, 5-benzoyl-4,6-dimethyl-1,2,3,4-tetrahydropyrimidine-2-thione and ethyl 6-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate, which are potential medicinals, are investigated using X-ray diffraction analysis. The conformational features of the molecules studied are analyzed.

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Authors and Affiliations

  1. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, Moscow, 119991, Russia

    G. V. Gurskaya

  2. Karpov Research Institute of Physical Chemistry, State Scientific Center, ul. Vorontsovo pole 10, Moscow, 103064, Russia

    V. E. Zavodnik

  3. Lomonosov State Academy of Fine Chemical Technology, pr. Vernadskogo 86, Moscow, 117571, Russia

    A. D. Shutalev

Authors
  1. G. V. Gurskaya
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  2. V. E. Zavodnik
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  3. A. D. Shutalev
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__________

Translated from Kristallografiya, Vol. 48, No. 3, 2003, pp. 461–466.

Original Russian Text Copyright © 2003 by Gurskaya, Zavodnik, Shutalev.

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Gurskaya, G.V., Zavodnik, V.E. & Shutalev, A.D. X-ray diffraction studies of 5-functionalized 1,2,3,4-tetrahydropyrimidin-2-ones(thiones): II. Molecular and crystal structures of 5-benzoyl-4,6-dimethyl-1,2,3,4-tetrahydropyrimidine-2-thione and ethyl 6-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate. Crystallogr. Rep. 48, 416–421 (2003). https://doi.org/10.1134/1.1578125

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  • DOI: https://doi.org/10.1134/1.1578125

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