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Transient ischemic dilation: A powerful diagnostic and prognostic finding of stress myocardial perfusion imaging

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Journal of Nuclear Cardiology Aims and scope

Summary

TID is an abnormal finding in stress myocardial perfusion imaging that suggests severe and extensive CAD and signifies a worse prognosis. TID has been reported with exercise and pharmacologic stress testing, planar and SPECT imaging, and Tl-201, Tc-99m, and dual-isotope protocols. Underlying mechanisms include a combination of stress-induced subendocardial hypoperfusion, ischemic systolic dysfunction, and less likely physical LV dilation with severe ischemia. TID appears to represent a significant ischemic burden and, compared with increased pulmonary Tl-201 uptake, suggests less permanent LV dysfunction and more myocardium at risk. Stress-to-rest LV volume ratios of 1.12 (epicardial) and 1.22 (endocardial) have been consistently shown to be highly specific for severe and extensive CAD.

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Authors and Affiliations

  1. Cardiovascular Division, Department of Medicine, 330 Brookline Ave, 02215, Boston, MA

    Michael G. McLaughlin

  2. Deaconess Medical Center and Harvard Medical School, Boston, MA.

    Peter G. Danias

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  1. Michael G. McLaughlin
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  2. Peter G. Danias
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Correspondence to Peter G. Danias.

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McLaughlin, M.G., Danias, P.G. Transient ischemic dilation: A powerful diagnostic and prognostic finding of stress myocardial perfusion imaging. J Nucl Cardiol 9, 663–667 (2002). https://doi.org/10.1067/mnc.2002.124979

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  • DOI: https://doi.org/10.1067/mnc.2002.124979

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