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Dose dependence of DNA repair in rainbow trout (Oncorhynchus mykiss) larvae exposed to UV-B radiation

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Abstract

We examined survival and DNA damage in rainbow trout larvae (Oncorhynchus mykiss) resulting from a range of sublethal to lethal ultraviolet-B exposures in the presence and absence of photoreactivating radiation. We found that after low, sublethal UV-B exposures trout larvae are quite proficient at photoenzymatic repair but that this capacity decreases exponentially with the total incident UV-B dose. The relationship between the dose dependence of PER and trout development and vulnerability in fisheries and in the natural environment are discussed.

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Abbreviations

CPD:

Cyclobutane pyrimidine dimer

mb:

Megabase

NER:

Nucleotide excision repair

PER:

Photoenzymatic repair

PRR:

Photorepair radiation

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Authors and Affiliations

  1. Department of Carcinogenesis, The University of Texas MD Andersen Cancer Center, 1808 Park Road 1C, Smithville, TX, 78957, USA

    David L. Mitchell

  2. Department of Biology, Franklin & Marshall College, Lancaster, PA, 17604, USA

    Tristan Adams-Deutsch & Mark H. Olson

Authors
  1. David L. Mitchell
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  2. Tristan Adams-Deutsch
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  3. Mark H. Olson
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Correspondence to David L. Mitchell.

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Mitchell, D.L., Adams-Deutsch, T. & Olson, M.H. Dose dependence of DNA repair in rainbow trout (Oncorhynchus mykiss) larvae exposed to UV-B radiation. Photochem Photobiol Sci 8, 75–81 (2009). https://doi.org/10.1039/b807469k

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