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The Induction and Repair of DNA Photodamage in the Environment

  • Chapter
Environmental UV Photobiology

Abstract

Since its discovery in bacteria 25 years ago, DNA repair, particularly in response to damage induced by UV radiation, has been a major focus of molecular biology. The roles played by DNA damage and repair in the aging and carcinogenic processes have been of particular interest. More recently, degradation of stratospheric ozone and the resultant increase in UV-B radiation at the earth’s surface have focused our attention on the environmental effects of solar DNA damage. Although we have learned much about DNA damage tolerance mechanisms in prokaryotes and some lower eukaryotes, our understanding of the molecular events that determine biological effects of UVR in complex higher eukaryotes is far from complete.

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Author information

Authors and Affiliations

  1. Department of Carcinogenesis, Science Park/Research Division, University of Texas System Cancer Center, Smithville, Texas, 78957, USA

    David L. Mitchell

  2. Department of Biology, University of San Francisco, San Francisco, California, 94117, USA

    Deneb Karentz

Authors
  1. David L. Mitchell
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  2. Deneb Karentz
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Editor information

Editors and Affiliations

  1. St. John’s Institute of Dermatology, London, UK

    Antony R. Young

  2. The Norwegian Radium Hospital, Oslo, Norway

    Johan Moan

  3. Lund University, Lund, Sweden

    Lars Olof Björn

  4. Philipps University, Marburg, Germany

    Wilhelm Nultsch

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© 1993 Springer Science+Business Media New York

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Mitchell, D.L., Karentz, D. (1993). The Induction and Repair of DNA Photodamage in the Environment. In: Young, A.R., Moan, J., Björn, L.O., Nultsch, W. (eds) Environmental UV Photobiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-2406-3_12

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  • DOI: https://doi.org/10.1007/978-1-4899-2406-3_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-2408-7

  • Online ISBN: 978-1-4899-2406-3

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