Skip to main content
SpringerLink
Log in

The photobleaching of disulfonated aluminium phthalocyanine in microbial systems

  • Published:
Photochemical & Photobiological Sciences Aims and scope Submit manuscript

Abstract

Front-face illumination spectroscopic techniques were used to study photobleaching of disulfonated aluminium phthalocyanine (AlPcS2) in the bacteria and yeast cells Escherichia coli, Porphyromonas gingivalis (Gram-negative bacteria), Streptococcus mutans (a Gram-positive bacterium), and the yeast Candida albicans. The photobleaching of AlPcS2 with the microbes studied is complex, involving reactive species generated by type I and type II processes with the rate dependent on the relative contributions of the different photobleaching mechanisms. The average rate of photobleaching of the AlPcS2 monomer in the presence of both E. coli and C. albicans increases as the fluence of the illumination source decreases. The effects of oxygen and sensitiser concentration on the rate of AlPcS2 photobleaching in these systems are also investigated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. T. S. Mang Photochem. Photobiol. 1987 45 501

    Article  CAS  Google Scholar 

  2. K. Konig, H. Wabnitz and W. Dietel J. Photochem. Photobiol., B 1990 8 103

    Article  CAS  Google Scholar 

  3. L. W. Ma, J. Moan and K. Berg Lasers Med. Sci. 1994 9 127

    Article  Google Scholar 

  4. J. Moan, C. Remington and Z. Malik Photochem. Photobiol. 1988 47 363

    Article  CAS  Google Scholar 

  5. J. Moan Lasers Med. Sci. 1989 3 93

    Article  Google Scholar 

  6. I. Georgakoudi and T. H. Foster Photochem. Photobiol. 1998 67 612

    CAS  PubMed  Google Scholar 

  7. J. D. Spikes Photochem. Photobiol. 1992 55 797

    Article  CAS  Google Scholar 

  8. G. S. Cox, M. Kreig and D. G. Whitten J. Am. Chem. Soc. 1982 104 6930

    Article  CAS  Google Scholar 

  9. A. A. Krasnovskii, Y. A. Veenediktov and O. M. Chernenko Biophysics (Engl. Transl.) 1982 27 1009

    Google Scholar 

  10. M. Kreig and D. G. Whitten J. Photochem. 1984 25 235

    Article  Google Scholar 

  11. B. McIlroy Spectroscopic studies of photodynamic therapy related to real-time monitoring of dosimetry, PhD Thesis, University of London, 1998

    Google Scholar 

  12. C. Hadjur, N. Lange, J. Rebstein, P. Monnier, H. van den Bergh and G. Wagnieres J. Photochem. Photobiol., B 1998 45 170

    Article  CAS  Google Scholar 

  13. M. Ambroz, A. Beeby, A. J. MacRobert, M. S. C. Simpson, R. K. Svensen and D. Phillips J. Photochem. Photobiol., B 1991 9 87

    Article  CAS  Google Scholar 

  14. R. B. Ostler, A. D. Scully, A. G. Taylor, I. R. Gould, T. A. Smith, A. Waite and D. Phillips Photochem. Photobiol. 2000 83 1

    Google Scholar 

  15. M. Pardekooper, A. E. van Gompl, H. J. G. M. De Bont, J. F. Nagelkerke, J. van Steveninck, P. J. A. van den Broek Photochem. Photobiol. 1994 59 161

    Article  Google Scholar 

  16. A. Western and J. Moan, in Light Biology and Medicine, eds. R. H. Douglas, J. Moan and F. Dall’acqna, 1988, Plenum Press, NY, pp. 85–89

  17. T. Burns, M. Wilson and G. J. Pearson, in SPIE Conference Proceedings “Photochemotherapy”, eds.B. Ehrenberg,G. Jori andJ. Moan, 1996, p. 288

  18. T. C. Oldham, Spectroscopic investigations of photodynamic mechanisms in cell cultures, PhD Thesis, University of London, 1996

    Google Scholar 

  19. S. Dhami, J. J. Cosa, S. M. Bishop and D. Phillips Langmuir 1996 12 293

    Article  CAS  Google Scholar 

  20. M. Ambroz, A. J. MacRobert, J. Morgan, G. Rumbles, M. S. C. Foley and D. Phillips J. Photochem. Photobiol., B 1994 22 105

    Article  CAS  Google Scholar 

  21. J. A. Lacey and D. Phillips J. Photochem. Photobiol., A 2001 142 145

    Article  CAS  Google Scholar 

  22. J. A. Lacey, Spectroscopic studies of phthalocyanine photochemistry in microbes, PhD Thesis, University of London, 1999

    Google Scholar 

  23. T. C. Oldham and D. Phillips J. Phys. Chem. 1999 103 9333

    Article  CAS  Google Scholar 

  24. B. M. Aveline and R. W. Redmond Photochem. Photobiol. 1998 68 256

    Google Scholar 

  25. C. Schoeneich and K. D. Asmus Radiat. Environ. Biophys. 1990 29 263

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, Imperial College of Science, Technology and Medicine, London, UK

    Jackie A. Lacey & David Phillips

Authors
  1. Jackie A. Lacey
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. David Phillips
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to David Phillips.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lacey, J.A., Phillips, D. The photobleaching of disulfonated aluminium phthalocyanine in microbial systems. Photochem Photobiol Sci 1, 120–125 (2002). https://doi.org/10.1039/b108828a

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1039/b108828a

Search

Navigation