Skip to main content
Log in

MLL methylation is not likely a common mechanism for therapy-related AML

  • Correspondence
  • Published:
Leukemia Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1

References

  1. Schmid M, Haaf T, Grunert D . 5-Azacytidine-induced undercondensations in human chromosomes. Hum Genet 1984; 67: 257–263.

    Article  CAS  Google Scholar 

  2. Wahlfors J, Hiltunen H, Heinonen K, Hamalainen E, Alhonen L, Janne J . Genomic hypomethylation in human chronic lymphocytic leukemia. Blood 1992; 80: 2074–2080.

    CAS  PubMed  Google Scholar 

  3. Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW et al. Induction of tumors in mice by genomic hypomethylation. Science 2003; 300: 489–492.

    Article  CAS  Google Scholar 

  4. Eden A, Gaudet F, Waghmare A, Jaenisch R . Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003; 300: 455.

    Article  CAS  Google Scholar 

  5. Collins FS, Brooks LD, Chakravarti A . A DNA polymorphism discovery resource for research on human genetic variation. Genome Res 1998; 8: 1229–1231.

    Article  CAS  Google Scholar 

  6. Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB . Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996; 93: 9821–9826.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to M V Relling.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bogni, A., Pui, CH. & Relling, M. MLL methylation is not likely a common mechanism for therapy-related AML. Leukemia 19, 1291–1292 (2005). https://doi.org/10.1038/sj.leu.2403768

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.leu.2403768

  • Springer Nature Limited

Navigation