Skip to main content

Advertisement

Log in

MULTIOMICS

A multiomic atlas for the exploration of healthy aging in human monocytes

  • News & Views
  • Published:

From Nature Aging

View current issue Submit your manuscript

An extensive multiomic resource using human monocytes reveals large-scale remodeling of DNA methylation landscapes in healthy aging and accelerated or pathological aging contexts. This work provides an invaluable resource with important implications for the study of age-related changes in immune function.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1: An atlas of immune aging in healthy men.

References

  1. Pera, A. et al. Maturitas 82, 50–55 (2015).

    Article  CAS  Google Scholar 

  2. Lopez-Otin, C., Blasco, M. A., Partridge, L., Serrano, M. & Kroemer, G. Cell 153, 1194–1217 (2013).

    Article  CAS  Google Scholar 

  3. Franceschi, C. & Campisi, J. J. Gerontol. A Biol. Sci. Med. Sci. 69(Suppl. 1), S4–S9 (2014).

  4. Shchukina, I. et al. Nat. Aging https://doi.org/10.1038/s43587-020-00002-6 (2020).

  5. Benayoun, B. A., Pollina, E. A. & Brunet, A. Nat. Rev. Mol. Cell Biol. 16, 593–610 (2015).

    Article  CAS  Google Scholar 

  6. Horvath, S. & Raj, K. Nat. Rev. Genet. 19, 371–384 (2018).

    Article  CAS  Google Scholar 

  7. Teschendorff, A. E., West, J. & Beck, S. Hum. Mol. Genet. 22, R7–R15 (2013).

    Article  CAS  Google Scholar 

  8. Sampathkumar, N. K. et al. Hum. Genet. 139, 333–356 (2020).

    Article  Google Scholar 

  9. Marquez, E. J. et al. Nat. Commun. 11, 751 (2020).

    Article  CAS  Google Scholar 

  10. Kovats, S. Cell. Immunol. 294, 63–69 (2015).

    Article  CAS  Google Scholar 

  11. Horvath, S. et al. Genome Biol. 17, 171 (2016).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Bérénice A. Benayoun.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kim, M., Benayoun, B.A. A multiomic atlas for the exploration of healthy aging in human monocytes. Nat Aging 1, 19–21 (2021). https://doi.org/10.1038/s43587-020-00007-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s43587-020-00007-1

  • Springer Nature America, Inc.

Navigation