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Light-sheet microscopy at high resolution

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An improved light-sheet microscope images live cells at sub-100-nm axial resolution.

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Fig. 1: Three-dimensional interferometric lattice light-sheet imaging.

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Acknowledgements

The author is grateful for funding by the National Institutes of Health (R35GM133522) and thanks James Manton for help simulating the 4Pi point spread function used in Fig. 1b,d.

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Correspondence to Reto Fiolka.

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Fiolka, R. Light-sheet microscopy at high resolution. Nat Biotechnol 39, 1345–1346 (2021). https://doi.org/10.1038/s41587-021-01101-4

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