The Catellani reaction is a multi-component cascade sequence, catalysed by palladium and norbornene, which typically uses aromatic starting materials. Now, through the use of a modified norbornene co-catalyst, the scope of this reaction has been extended to alkenyl reagents, enabling the preparation of all-carbon tetrasubstituted olefins.
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Panels b and c are adapted from ref. 4, Springer Nature Ltd
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Maestri, G., Derat, E. Alkenyl boost for Catellani. Nat. Chem. 11, 1082–1084 (2019). https://doi.org/10.1038/s41557-019-0361-3
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DOI: https://doi.org/10.1038/s41557-019-0361-3
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