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Assessing bone structure in the prediction of osteoporotic fractures

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Measuring bone structure could improve prediction of bone strength, but the clinical feasibility of available imaging technologies is limited. The trabecular bone score—a dual-energy X-ray absorptiometry texture algorithm—has shown promise in fracture prediction in a large cohort study, and might provide a practical means of assessing bone quality.

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Figure 1: The effect of confounding factors on DXA images.

References

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  1. Department of Radiology and Biomedical Imaging, University of California, San Francisco, 400 Parnassus Avenue, A-367, Box 0628, San Francisco, 94131, CA, USA

    Thomas M. Link

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  1. Thomas M. Link
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Link, T. Assessing bone structure in the prediction of osteoporotic fractures. Nat Rev Rheumatol 8, 6–8 (2012). https://doi.org/10.1038/nrrheum.2011.174

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