Abstract
Integrating a wide range of biomedical data such as that rapidly emerging from the use of next-generation sequencing is expected to have a key role in identifying and qualifying new biomarkers to support precision medicine. Here, we highlight some of the challenges for biomedical data integration and approaches to address them.
References
Marti-Solano, M. et al. Integrative knowledge management to enhance pharmaceutical R&D. Nat. Rev. Drug Discov. 13, 239–240 (2014).
Acknowledgements
P. Groth, J. Saric, P. Scordis, M. Grossman, J. Quackenbush, B. Williams-Jones, R. Schneider, and A. Pai gave presentations and are acknowledged together with the rest of the participants for their valuable input to the ideas in this article (see Supplementary information S1 (box)).
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The authors declare no competing financial interests.
Supplementary information
Supplementary information S1 (box)
Agenda and participants for “Data integration and biomarker translational research in pharmas” The workshop, organized by Bayer Pharma, was held on 10th-11th of March 2015 at the Maritim proArte Hotel, Berlin, Germany. (PDF 205 kb)
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Elefsinioti, A., Bellaire, T., Wang, A. et al. Key factors for successful data integration in biomarker research. Nat Rev Drug Discov 15, 369–370 (2016). https://doi.org/10.1038/nrd.2016.74
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DOI: https://doi.org/10.1038/nrd.2016.74
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