Sleep consolidates memory. By cuing specific memories during sleep, a study now links this consolidation of memory to the replay of neuronal ensemble activity that occurs in the hippocampus during slow-wave sleep after learning.
References
Rasch, B., Büchel, C., Gais, S. & Born, J. Science 315, 1426–1429 (2007).
Diekelmann, S., Büchel, C., Born, J. & Rasch, B. Nat. Neurosci. 14, 381–386 (2011).
Antony, J.W., Gobel, E.W., O'Hare, J.K., Reber, P.J. & Paller, K.A. Nat. Neurosci. 15, 1114–1116 (2012).
Diekelmann, S. & Born, J. Nat. Rev. Neurosci. 11, 114–126 (2010).
Wilson, M.A. & McNaughton, B.L. Science 265, 676–679 (1994).
Bendor, D. & Wilson, M.A. Nat. Neurosci. 15, 1439–1444 (2012).
Girardeau, G., Benchenane, K., Wiener, S.I., Buzsáki, G. & Zugaro, M.B. Nat. Neurosci. 12, 1222–1223 (2009).
Ego-Stengel, V. & Wilson, M.A. Hippocampus 20, 1–10 (2010).
Tononi, G. & Cirelli, C. Sleep Med. Rev. 10, 49–62 (2006).
Marshall, L., Helgadottir, H., Mölle, M. & Born, J. Nature 444, 610–613 (2006).
Rudoy, J.D., Voss, J.L., Westerberg, C.E. & Paller, K.A. Science 326, 1079 (2009).
Sirota, A., Csicsvari, J., Buhl, D. & Buzsáki, G. Proc. Natl. Acad. Sci. USA 100, 2065–2069 (2003).
Ji, D. & Wilson, M.A. Nat. Neurosci. 10, 100–107 (2007).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Kelemen, E., Born, J. Sleep tight, wake up bright. Nat Neurosci 15, 1327–1329 (2012). https://doi.org/10.1038/nn.3227
Published:
Issue Date:
DOI: https://doi.org/10.1038/nn.3227
- Springer Nature America, Inc.
This article is cited by
-
Multiple memories can be simultaneously reactivated during sleep as effectively as a single memory
Communications Biology (2021)