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Biomaterials

Thwarting thrombus

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A new generation of biocompatible materials may be on the horizon. Building or coating medical devices with materials that release the versatile bioregulatory agent, nitric oxide, can greatly improve their performance when in contact with tissues and physiological fluids.

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Figure 1: Biocompatibility improvement through diazeniumdiolation.
Figure 2: Stopping clot formation with NO-releasing materials.

Photographs are reproduced from Zhang et al.1 with permission.

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Authors and Affiliations

  1. Chemistry Section, Laboratory of Comparative Carcinogenesis, National Cancer Institute at Frederick, Frederick, 21702-1201, Maryland, USA

    Larry K. Keefer

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  1. Larry K. Keefer
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Keefer, L. Thwarting thrombus. Nature Mater 2, 357–358 (2003). https://doi.org/10.1038/nmat913

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