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Targeted cellular immunotherapy for T cell malignancies

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In a recent study, Maciocia et al. develop a novel T cell receptor beta (TCRB) constant C1-chain-directed cellular immunotherapy for the treatment of T cell malignancies.

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Figure 1: Principles of anti-TCRB-C1 CAR T cell therapy.

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Correspondence to Adolfo Ferrando.

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Palomero, T., Ferrando, A. Targeted cellular immunotherapy for T cell malignancies. Nat Med 23, 1402–1403 (2017). https://doi.org/10.1038/nm.4458

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