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Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry

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Acknowledgements

A full list of Acknowledgments is provided in the Supplementary Note.

Author information

Authors and Affiliations

  1. Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK

    Karen A Hunt, Vanisha Mistry, Nicholas A Bockett, Patrick C Dubois, Graham A R Heap & David A van Heel

  2. Department of Medical Genetics, Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK

    Deborah J Smyth, Jason D Cooper, Sarah Nutland, Corina Shtir, Neil M Walker & John A Todd

  3. Institute of Clinical Molecular Biology, Christian-Albrechts-Universität zu Kiel, Kiel, Germany

    Tobias Balschun, Sylvia Hofmann, Stefan Schreiber & Andre Franke

  4. Department of Clinical Neurosciences, Addenbrookes Hospital, University of Cambridge, Cambridge, UK

    Maria Ban & Stephen Sawcer

  5. Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK

    Tariq Ahmad

  6. Division of Genetics and Molecular Medicine, King's College London, London, UK

    Vidya Anand & Timothy J Vyse

  7. Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK

    Jeffrey C Barrett, Sarah Edkins, Sarah Hunt, Cordelia Langford, Willem Ouwehand, Simon Potter & Panos Deloukas

  8. Genome Centre, Barts and the London School of Medicine and Dentistry, John Vane Science Centre, London, UK

    Leena Bhaw-Rosun, Kerith-Rae M Dias & Charles A Mein

  9. Oxford Centre for Diabetes Endocrinology and Metabolism, University of Oxford and Oxford National Institute for Health Research (NIHR) Biomedical Centre, Oxford, UK

    Oliver J Brand, Matthew J Simmonds & Stephen C L Gough

  10. Department of Rheumatology and Clinical Immunology, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands

    Elisabeth Brouwer & Marcel D Posthumus

  11. Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA

    Patrick Concannon, Suna Onengut-Gumuscu & Stephen S Rich

  12. Genetics Department, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands

    Cleo C van Diemen, Karin Fransen, Gosia Trynka, Alexandra Zhernakova & Cisca Wijmenga

  13. Department of Dermatology, University Clinic Schleswig-Holstein, Campus Kiel, Kiel, Germany

    Regina Fölster-Holst & Stephan Weidinger

  14. Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA

    David N Glass, Marc Sudman & Susan D Thompson

  15. Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands

    Tom W J Huizinga, Rene Toes & Alexandra Zhernakova

  16. IBD Genetics Research Group, Addenbrooke's Hospital, Cambridge, UK

    James Lee & Miles Parkes

  17. Department of Gastroenterology & Hepatology, University of Newcastle upon Tyne, Royal Victoria Infirmary, Newcastle upon Tyne, UK

    John Mansfield

  18. Dipartimento di Scienze Neurologiche e Cardiovascolari, Centro Sclerosi Multipla, Università di Cagliari, Cagliari, Italy

    Maria Giovanna Marrosu

  19. Department of Medical and Molecular Genetics, King's College London School of Medicine, Guy's Hospital, London, UK

    Christopher G Mathew & Natalie J Prescott

  20. Department of Pneumology, University Medical Center, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany

    Joachim Müller-Quernheim

  21. Department of Haematology, University of Cambridge & National Health Service (NHS) Blood and Transplant, Cambridge, UK

    Willem Ouwehand & Jennifer Sambrook

  22. University College London Genomics, Institute of Child Health, University College London, London, UK

    Kerra Pearce

  23. Istituto di Neurologia Clinica, Università di Sassari, Sassari, Italy

    Giulio Rosati

  24. Division of Medical Sciences, Gastrointestinal Unit, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK

    Jack Satsangi

  25. Department of Dermatology and Allergy, Technical University Munich, Munich, Germany

    Stephan Weidinger

  26. Department of Medical Genetics, Complex Genetics Section, University Medical Centre Utrecht, Utrecht, The Netherlands

    Alexandra Zhernakova

  27. Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA

    Alexandra Zhernakova

  28. Dipartimento di Scienze Biomediche, Università di Sassari, Sassari, Italy

    Magdalena Zoledziewska & Francesco Cucca

  29. Department of Gastroenterology and Hepatology, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands

    Rinse K Weersma

  30. Istituto di Neurogenetica e Neurofarmacologia, Consiglio Natzionale delle Richerche (CNR), Monserrato, Italy

    Francesco Cucca

Authors
  1. Karen A Hunt
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  2. Deborah J Smyth
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  3. Tobias Balschun
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  4. Maria Ban
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  5. Vanisha Mistry
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  6. Tariq Ahmad
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  7. Vidya Anand
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  8. Jeffrey C Barrett
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  9. Leena Bhaw-Rosun
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  10. Nicholas A Bockett
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  11. Oliver J Brand
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  12. Elisabeth Brouwer
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  13. Patrick Concannon
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  14. Jason D Cooper
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  15. Kerith-Rae M Dias
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  16. Cleo C van Diemen
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  17. Patrick C Dubois
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  18. Sarah Edkins
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  19. Regina Fölster-Holst
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  20. Karin Fransen
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  21. David N Glass
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  22. Graham A R Heap
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  23. Sylvia Hofmann
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  24. Tom W J Huizinga
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  25. Sarah Hunt
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  26. Cordelia Langford
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  27. James Lee
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  28. John Mansfield
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  29. Maria Giovanna Marrosu
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  30. Christopher G Mathew
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  31. Charles A Mein
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  32. Joachim Müller-Quernheim
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  33. Sarah Nutland
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  34. Suna Onengut-Gumuscu
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  35. Willem Ouwehand
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  36. Kerra Pearce
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  37. Natalie J Prescott
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  38. Marcel D Posthumus
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  39. Simon Potter
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  40. Giulio Rosati
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  41. Jennifer Sambrook
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  42. Jack Satsangi
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  43. Stefan Schreiber
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  44. Corina Shtir
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  45. Matthew J Simmonds
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  46. Marc Sudman
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  47. Susan D Thompson
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  48. Rene Toes
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  49. Gosia Trynka
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  50. Timothy J Vyse
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  51. Neil M Walker
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  52. Stephan Weidinger
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  53. Alexandra Zhernakova
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  54. Magdalena Zoledziewska
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  55. Rinse K Weersma
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  56. Stephen C L Gough
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  57. Stephen Sawcer
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  58. Cisca Wijmenga
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  59. Miles Parkes
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  60. Francesco Cucca
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  61. Andre Franke
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  62. Panos Deloukas
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  63. Stephen S Rich
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  64. John A Todd
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  65. David A van Heel
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Consortia

Type 1 Diabetes Genetics Consortium

UK Inflammatory Bowel Disease (IBD) Genetics Consortium

Wellcome Trust Case Control Consortium

Corresponding author

Correspondence to David A van Heel.

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Competing interests

The authors declare no competing financial interests.

Additional information

A full list of consortium members is provided in the Supplementary Note.

A full list of consortium members is provided in the Supplementary Note.

A full list of consortium members is provided in the Supplementary Note.

Supplementary information

Supplementary Text and Figures

Supplementary Note and Supplementary Tables 1 and 2. (PDF 188 kb)

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Cite this article

Hunt, K., Smyth, D., Balschun, T. et al. Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry. Nat Genet 44, 3–5 (2012). https://doi.org/10.1038/ng.1037

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  • DOI: https://doi.org/10.1038/ng.1037

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