Skip to main content
SpringerLink
Log in

Stopping malaria parasites dead in their tracks

  • News & Views
  • Published:

From Nature Chemical Biology

View current issue Submit your manuscript

The search for new antimalarial strategies takes a step forward with the discovery of a small parasitocidal molecule that inhibits a calcium-dependent protein kinase and may thereby interfere with parasite motility.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: The roles of CDPKs in the life cycle of malaria parasites.

Kim Caesar

References

  1. Ventura, J.J. & Nebreda, A.R. Clin. Transl. Oncol. 8, 153–160 (2006).

    Article  CAS  Google Scholar 

  2. Kato, N. et al. Nat. Chem. Biol. 4, 347–356 (2008).

    Article  CAS  Google Scholar 

  3. Soldati, D. & Meissner, M. Curr. Opin. Cell Biol. 16, 32–40 (2004).

    Article  CAS  Google Scholar 

  4. Green, J.L. et al. J. Mol. Biol. 355, 933–941 (2006).

    Article  CAS  Google Scholar 

  5. Dorin-Semblat, D. et al. Mol. Microbiol. 65, 1170–1180 (2007).

    Article  CAS  Google Scholar 

  6. Davies, S.P., Reddy, H., Caivano, M. & Cohen, P. Biochem. J. 351, 95–105 (2000).

    Article  CAS  Google Scholar 

  7. Bishop, A.C., Buzko, O. & Shokat, K.M. Trends Cell Biol. 11, 167–172 (2001).

    Article  CAS  Google Scholar 

  8. Billker, O. et al. Cell 117, 503–514 (2004).

    Article  CAS  Google Scholar 

  9. Ishino, T., Orito, Y., Chinzei, Y. & Yuda, M. Mol. Microbiol. 59, 1175–1184 (2006).

    Article  CAS  Google Scholar 

  10. Coppi, A. et al. Cell Host Microbe 2, 316–327 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Christian D. Doerig is at Institut National de la Santé et de la Recherche Médicale Unit 609, Wellcome Centre for Molecular Parasitology, University of Glasgow Biomedical Research Centre, 120 University Place, Glasgow, Scotland G12 8TA, UK. cdoer001@udcf.gla.ac.uk ,

    Christian D Doerig

Authors
  1. Christian D Doerig
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Doerig, C. Stopping malaria parasites dead in their tracks. Nat Chem Biol 4, 334–335 (2008). https://doi.org/10.1038/nchembio0608-334

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchembio0608-334

  • Springer Nature America, Inc.

Search

Navigation