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Cycloparaphenylenes

Closing the loop

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The synthesis of [5]CPP, the smallest and by far the most strained member of the family of macrocycles known as cycloparaphenylenes, has been reported in quick succession by two different research groups. But how long will the new record holder retain its title?

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Figure 1: Strained hydrocarbon hoops.
Figure 2: The final few steps of the syntheses of [5]CPP as reported by the groups of Jasti1 and Yamago2.

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Correspondence to Graham J. Bodwell.

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Bodwell, G. Closing the loop. Nature Chem 6, 383–385 (2014). https://doi.org/10.1038/nchem.1932

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