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Cancer sequencing unravels clonal evolution

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Characterization of tumor heterogeneity at the sequence level presents new challenges and opportunities for targeted therapies.

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Figure 1: Clonal evolution in primary tumors and metastases (adapted from ref. 1).

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Authors and Affiliations

  1. Carlos Caldas is in the Department of Oncology at the University of Cambridge and at Cancer Research UK, Cambridge Research Institute, Cambridge, UK.,

    Carlos Caldas

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  1. Carlos Caldas
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Correspondence to Carlos Caldas.

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The author declares no competing financial interests.

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Caldas, C. Cancer sequencing unravels clonal evolution. Nat Biotechnol 30, 408–410 (2012). https://doi.org/10.1038/nbt.2213

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