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Immunology

B-cell development in the gut

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B cells arise in the bone marrow and go on to produce antibodies that protect against microbial infection. Surprisingly, it seems that B-cell development also occurs in the gut, where it is stimulated by resident microbes. See Letter p.112

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Figure 1: Receptor editing.

Notes

  1. *This article and the paper under discussion4 were published online on 21 August 2013.

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Authors and Affiliations

  1. Mark Schlissel is in the Departments of Molecular Biology, Cell Biology, and Biochemistry and Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island 02912, USA.,

    Mark Schlissel

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  1. Mark Schlissel
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Correspondence to Mark Schlissel.

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Schlissel, M. B-cell development in the gut. Nature 501, 42–43 (2013). https://doi.org/10.1038/nature12551

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