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The ylide has landed

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The enzyme co-substrate SAM has long been known to have two chemically distinct roles. A study of the CmoA enzyme suggests that SAM has a third trick up its sleeve — it forms species known as ylides. See Letter p.123

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Figure 1: An ylide biosynthetic intermediate.

Notes

  1. *This article and the paper under discussion3 were published online on 15 May 2013.

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Authors and Affiliations

  1. Bradley J. Landgraf and Squire J. Booker are in the Departments of Chemistry and of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.,

    Bradley J. Landgraf & Squire J. Booker

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  1. Bradley J. Landgraf
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  2. Squire J. Booker
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Correspondence to Squire J. Booker.

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Landgraf, B., Booker, S. The ylide has landed. Nature 498, 45–47 (2013). https://doi.org/10.1038/nature12247

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