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Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target

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Acknowledgements

This work is supported by grants from the Leukemia Research Foundation (GA), National Institutes of Health National Cancer Institute (P50CA100632) (GA) and Leukemia & Lymphoma Society (GA and SK).

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Author notes

  1. H R Garber and M Zhang: These authors contributed equally to this work.

Authors and Affiliations

  1. Department of Stem Cell Transplantation and Cellular Therapy, Section of Transplant Immunology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA

    G Alatrash, H R Garber, M Zhang, P Sukhumalchandra, H Jakher, A A Perakis, L Becker, K C Dwyer, L S St John, A Sergeeva, H He, Q Ma & J J Molldrem

  2. Department of Leukemia, MD Anderson Cancer Center, Houston, TX, USA

    Y Qiu & S M Kornblau

  3. Department of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston, TX, USA

    S Y Yoo

  4. Department of Biomedical Informatics, Ohio State University, Columbus, OH, USA

    K Coombes

  5. Department of Melanoma Medical Oncology, MD Anderson Cancer Center, Houston, TX, USA

    A H Talukder, J Roszik & G Lizee

  6. Department of Pediatrics, MD Anderson Cancer Center, Houston, TX, USA

    V Senyukov & D A Lee

  7. Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA

    P M Armistead

  8. Department of Genomic Medicine, MD Anderson Cancer Center, Houston, TX, USA

    J Roszik

  9. Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX, USA

    E A Mittendorf

  10. Department of Systems Biology, MD Anderson Cancer Center, Houston, TX, USA

    D Hawke

Authors
  1. G Alatrash
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  2. H R Garber
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  3. M Zhang
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  4. P Sukhumalchandra
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  7. A A Perakis
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  8. L Becker
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  9. S Y Yoo
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  10. K C Dwyer
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  11. K Coombes
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  13. L S St John
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  14. V Senyukov
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  15. D A Lee
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  16. A Sergeeva
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  17. H He
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  18. Q Ma
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  19. P M Armistead
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  20. J Roszik
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  21. E A Mittendorf
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  22. J J Molldrem
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  23. D Hawke
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  24. G Lizee
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  25. S M Kornblau
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Corresponding author

Correspondence to G Alatrash.

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The authors declare no conflict of interest.

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Supplementary Information accompanies this paper on the Leukemia website

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Alatrash, G., Garber, H., Zhang, M. et al. Cathepsin G is broadly expressed in acute myeloid leukemia and is an effective immunotherapeutic target. Leukemia 31, 234–237 (2017). https://doi.org/10.1038/leu.2016.249

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