Skip to main content
Log in

Fermented lactotripeptides-containing milk lowers daytime blood pressure in high normal-to-mild hypertensive subjects

  • Research Letter
  • Published:
Journal of Human Hypertension Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1

References

  1. Aihara K, Kajimoto O, Hirata H, Takahashi R, Nakamura Y . Effect of powdered fermented milk with Lactobacillus helveticus on subjects with high-normal blood pressure or mild hypertension. J Am Coll Nutr 2005; 24: 257–265.

    Article  Google Scholar 

  2. Hata Y, Yamamoto M, Ohni M, Nakajima K, Nakamura Y, Takano T . A placebo-controlled study of the effect of sour milk on blood pressure in hypertensive subjects. Am J Clin Nutr 1996; 64: 767–771.

    Article  CAS  Google Scholar 

  3. Nakamura Y, Kajimoto O, Kaneko K, Aihara K, Mizutani J, Ikeda N et al. Effects of the liquid yoghurts containing ‘lactotripeptides (VPP,IPP)’ on high-normal blood pressure. J Nutr Food 2004; 7: 123–137.

    Google Scholar 

  4. Jauhiainen T, Vapaatalo H, Poussa T, Kyronpalo S, Rasmussen M, Korpela R . Lactobacillus helveticus fermented milk lowers blood pressure in hypertensive subjects in 24-h ambulatory blood pressure measurement. Am J Hypertens 2005; 18: 1600–1605.

    Article  Google Scholar 

  5. Mizuno S, Matsuura K, Gotou T, Nishimura S, Kajimoto O, Yabune M et al. Antihypertensive effect of casein hydrolyzate prepared using an Aspergillus oryzae protease in a placebo-controlled clinical study for subjects with high-normal blood pressure and mild-hypertension. Br J Nutr 2005; 94: 84–91.

    Article  CAS  Google Scholar 

  6. Mizushima S, Ohshige K, Watanabe J, Kimura M, Kadowaki T, Nakamura Y et al. Randomized controlled trial of sour milk on blood pressure in borderline hypertensive men. Am J Hypertens 2004; 17: 701–706.

    Article  Google Scholar 

  7. Sano J, Ohki K, Higuchi T, Aihara K, Mizuno S, Kajimoto O et al. Effect of casein hydrolysate, prepared with protease derived from Aspergillus oryzae, on subjects with high-normal blood pressure or mild hypertension. J Med Food 2005; 8: 423–430.

    Article  CAS  Google Scholar 

  8. Seppo L, Jauhiainen T, Poussa T, Korpela R . A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects. Am J Clin Nutr 2003; 77: 326–330.

    Article  CAS  Google Scholar 

  9. Tuomilehto J, Lindstrom J, Hyyrynen J, Korpela R, Karhunen ML, Mikkola L et al. Effect of ingesting sour milk fermented using Lactobacillus helveticus bacteria producing tripeptides on blood pressure in subjects with mild hypertension. J Hum Hypertens 2004; 18: 795–802.

    Article  CAS  Google Scholar 

  10. Nakamura Y, Yamamoto N, Sakai K, Takano T . Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme. J Dairy Sci 1995; 78: 1253–1257.

    Article  CAS  Google Scholar 

  11. Nakamura Y, Yamamoto N, Sakai K, Okubo A, Yamazaki S, Takano T . Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J Dairy Sci 1995; 78: 777–783.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K van der Zander.

Additional information

Supplementary Information accompanies the paper on the Journal of Human Hypertension website (http://www.nature.com/jhh)

Supplementary information

Rights and permissions

Reprints and permissions

About this article

Cite this article

van der Zander, K., Jäkel, M., Bianco, V. et al. Fermented lactotripeptides-containing milk lowers daytime blood pressure in high normal-to-mild hypertensive subjects. J Hum Hypertens 22, 804–806 (2008). https://doi.org/10.1038/jhh.2008.59

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/jhh.2008.59

  • Springer Nature Limited

This article is cited by

Navigation