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Kinesin–ADP: whole lotta shakin' goin' on

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A mobile state of the kinesin–ADP head is discovered using multi- and single-molecule fluorescence polarization.

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Figure 1: Atomic models of tubulin and conventional kinesin fit into a wire-frame electron density image of a microtubule decorated with KIF1A calculated from cryo-EM data12.
Figure 2: Sensitivity to orientational motions in ensemble and single molecule measurements.

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Authors and Affiliations

  1. the Department of Physiology and Pennsylvania Muscle Institute, University of Pennsylvania, Philadelphia, 19104-6083, Pennsylvania, USA

    Margot E. Quinlan, Joseph N. Forkey & Yale E. Goldman

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  1. Margot E. Quinlan
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  2. Joseph N. Forkey
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  3. Yale E. Goldman
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Correspondence to Yale E. Goldman.

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Quinlan, M., Forkey, J. & Goldman, Y. Kinesin–ADP: whole lotta shakin' goin' on. Nat Struct Mol Biol 8, 478–480 (2001). https://doi.org/10.1038/88522

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