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Class (I) will come to order – not

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Structures of several structurally and functionally divergent MHC class I homologs and receptor complexes have recently been determined. They reveal the unusual versatility of the underlying MHC class I fold.

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Figure 1: The structure of a classical MHC class I protein.
Figure 2: Footprints of protein ligands on several MHC class I molecules.
Figure 3: Superpositions of the platform domains of HLA-A2 (red), MIC-A (blue) and H-2T22b (purple) in the same orientation as in Fig. 1c.
Figure 4: Space-filling representations of the structures of MIC-A (top) and H-2T22b (bottom).

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  1. Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, 98109, Washington, USA

    Roland K. Strong

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  1. Roland K. Strong
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Strong, R. Class (I) will come to order – not. Nat Struct Mol Biol 7, 173–176 (2000). https://doi.org/10.1038/73254

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