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HIV

Going for the watchman

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A protein called SAMHD1 seems to hinder the infection of key cells of the immune system by HIV-1. Cousins of this virus, however, produce a factor that overcomes the protective effects of SAMHD1. See Letters p.654 & p.658

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Figure 1: Vpx, SAMHD1 and viral replication1,2.

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Authors and Affiliations

  1. Efrem S. Lim is in the Department of Microbiology, University of Washington, Seattle, Washington 98195-7242, USA.,

    Efrem S. Lim

  2. Michael Emerman is in the Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.,

    Michael Emerman

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  1. Efrem S. Lim
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  2. Michael Emerman
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Correspondence to Michael Emerman.

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Lim, E., Emerman, M. Going for the watchman. Nature 474, 587–588 (2011). https://doi.org/10.1038/474587a

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