Skip to main content
SpringerLink
Log in

Molecular biology

The expanding arena of DNA repair

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

The protein Sae2 mediates the repair of double-strand breaks in DNA. It emerges that Sae2 activity is controlled by both its modification with acetyl groups and its degradation by the process of autophagy. See Article p.74

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Possible role of Sae2 in DNA-damage repair1.

References

  1. Robert, T. et al. Nature 471, 74–79 (2011).

    Article  ADS  CAS  Google Scholar 

  2. Göttlicher, M. et al. EMBO J. 20, 6969–6978 (2001).

    Article  Google Scholar 

  3. Mimitou, E. P. & Symington, L. S. DNA Repair doi:10.1016/j.dnarep.2010.12.004 (2011).

    Google Scholar 

  4. Choudhary, C. et al. Science 325, 834–840 (2009).

    Article  ADS  CAS  Google Scholar 

  5. Kaidi, A., Weinert, B. T., Choudhary, C. & Jackson, S. P. Science 329, 1348–1353 (2010).

    Article  ADS  CAS  Google Scholar 

  6. Shao, Y., Gao, Z., Marks, P. A. & Jiang, X. Proc. Natl Acad. Sci. USA 101, 18030–18035 (2004).

    Article  ADS  CAS  Google Scholar 

  7. Fu, J., Shao, C.-J., Chen, F.-R., Ng, H.-K. & Chen, Z.-P. Neuro-Oncology 12, 328–340 (2010).

    Article  CAS  Google Scholar 

  8. Degenhardt, K. et al. Cancer Cell 10, 51–64 (2006).

    Article  CAS  Google Scholar 

  9. Nagai, S. et al. Science 322, 597–602 (2008).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Catherine J. Potenski and Hannah L. Klein are in the Department of Biochemistry, New York University School of Medicine, New York, New York 10016, USA.,

    Catherine J. Potenski & Hannah L. Klein

Authors
  1. Catherine J. Potenski
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hannah L. Klein
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hannah L. Klein.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Potenski, C., Klein, H. The expanding arena of DNA repair. Nature 471, 48–49 (2011). https://doi.org/10.1038/471048a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/471048a

  • Springer Nature Limited

This article is cited by

Search

Navigation