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How B and T cells talk to each other

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Abstract

The B cells of the immune system, which secrete antibodies against foreign antigens, are fully specific and effective only after maturation in lymph nodes and other lymphoid tissues. Immunocompetent T cells play a crucial part in this process, but the molecular details of the way in which the two cell types interact have only recently become apparent.

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Authors and Affiliations

  1. Department of Microbiology and Regional Primate Research Center, University of Washington Medical Center, SC-42, Seattle, Washington, 98195, USA

    Edward A. Clark

  2. Bristol-Myers Squibb Pharmaceutical Research Institute, 3005 First Avenue, Seattle, Washington, 98121, USA

    Jeffrey A. Ledbetter

Authors
  1. Edward A. Clark
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  2. Jeffrey A. Ledbetter
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Clark, E., Ledbetter, J. How B and T cells talk to each other. Nature 367, 425–428 (1994). https://doi.org/10.1038/367425a0

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