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Nutrition

Antioxidant activity of fresh apples

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Abstract

Vitamin C is used as a dietary supplement because of its antioxidant activity, although a high dose (500 mg) may act as a pro-oxidant in the body1,2. Here we show that 100 g of fresh apples has an antioxidant activity equivalent to 1,500 mg of vitamin C, and that whole-apple extracts inhibit the growth of colon- and liver- cancer cells in vitro in a dose-dependent manner. Our results indicate that natural antioxidants from fresh fruit could be more effective than a dietary supplement.

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Figure 1: Antioxidant activity of apples and their effect on tumour-cell proliferation in vitro.

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References

  1. Podmore, I. D. et al. Nature 392, 559 ( 1998).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Herbert, V. et al. J. Nutr. 126, 1213S– 1220S (1996).

    Article  CAS  PubMed  Google Scholar 

  3. Singleton, V. L. & Rossi, J. A. Jr Am. J. Enol. Viticult. 16, 144–158 (1965).

    CAS  Google Scholar 

  4. Zhisen, J., Mengcheng, T. & Jianming, W. Food Chem. 64, 555– 559 (1999).

    Article  Google Scholar 

  5. Burda, S., Oleszek, W. & Lee, C. Y. J. Agric. Food Chem. 38, 945– 948 (1990).

    Article  CAS  Google Scholar 

  6. Winston, G. W., Regoli, F., Dugas, A. J., Fong, J. H. & Blanchard, K. A. Free Rad. Biol. Med. 24, 480 –493 (1998).

    Article  CAS  PubMed  Google Scholar 

  7. USDA Nutrient Database for Standard Reference ( 1998).

  8. Wang, H., Cao, G. & Prior, R. L. J. Agric. Food Chem. 44, 701– 705 (1998).

    Article  Google Scholar 

  9. Lunec, J. J. Int. Fed. Clin. Chem. 4, 58–63 (1992).

    CAS  Google Scholar 

  10. Cory, A. H., Owen, T. C., Barltrop, J. A. & Cory, J. G. Cancer Commun. 3, 207–212 (1991).

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Rui Hai Liu.

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Eberhardt, M., Lee, C. & Liu, R. Antioxidant activity of fresh apples. Nature 405, 903–904 (2000). https://doi.org/10.1038/35016151

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